Evidence map›Paper›PMID 27050708›Full record

ArticleAIDS care2016

The role of chronic pain and current substance use in predicting negative social support among disadvantaged persons living with HIV/AIDS.

Mary M Mitchell, Allysha C Maragh-Bass, Trang Q Nguyen, Sarina Isenberg, Amy R Knowlton

Open access · greenAbstract read
In one paragraph

Article in AIDS care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mary M Mitchella Department of Health, Behavior and Society , Johns Hopkins Bloomberg School of Public Health , Baltimore , MD , USA.
Allysha C Maragh-Bassb Department of Surgery, Harvard School of Medicine, Harvard School of Public Health, Center for Surgery and Public Health , Brigham and Women's Hospital , Boston , MA , USA.
Trang Q Nguyenc Department of Mental Health , Johns Hopkins Bloomberg School of Public Health , Baltimore , MD , USA.
Sarina Isenberga Department of Health, Behavior and Society , Johns Hopkins Bloomberg School of Public Health , Baltimore , MD , USA.
Amy R Knowltona Department of Health, Behavior and Society , Johns Hopkins Bloomberg School of Public Health , Baltimore , MD , USA.
Johns Hopkins University · USBrigham and Women's Hospital · US

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
NIDA Epidemiology Training Program: Johns Hopkins UniversityT32DA007292 · NIDA · JOHNS HOPKINS UNIVERSITY · PI RENEE M. JOHNSON, Brion S Maher · 1993 to 2026
$17.7M
Sustaining palliative care to drug users with HIV/AIDS & health disparitiesR01NR014050 · NINR · JOHNS HOPKINS UNIVERSITY · PI KNOWLTON, AMY · 2013 to 2017
$2.3M
Informal Caregiving & Medical Adherence Among HIV+ IDUsR01DA019413 · NIDA · JOHNS HOPKINS UNIVERSITY · PI KNOWLTON, AMY · 2006 to 2009
$2.2M
NIAID NIH HHS P30 AI094189NIDA NIH HHS R01 DA019413NIDA NIH HHS T32 DA007292NINR NIH HHS R01 NR014050
6 · The paper itself

Abstract

Chronic pain and substance use can strain the supportive relationships of persons with serious chronic illness, which may increase the likelihood of receiving negative, rather than positive, social support from informal caregivers and social network members. To our knowledge, this is the first study to longitudinally examine the effects of chronic pain and substance use on negative social support. The sample (N = 383) comprised disadvantaged, primarily African-American, persons living with HIV/AIDS with a history of injection drug use, 32.4% of whom reported frequent or constant pain in the prior 6 months. Using factor analysis and structural equation modeling, current substance use and greater levels of chronic pain positively predicted negative social support 12 months later, after controlling for baseline negative support, viral load, age and sex. We also found a significant interaction effect such that among those not using substances, there was a significant positive association between pain and negative support, but no such association among those currently using substances. The findings emphasize the importance of treatment of chronic pain and substance use in the supportive functioning of social networks of a disadvantaged population with serious chronic conditions and persistent health disparities.

Indexed as

Social SupportVulnerable PopulationsAdultCaregiversChronic PainFemaleHIV InfectionsHumansLongitudinal StudiesMaleMiddle AgedSubstance Abuse, Intravenousblack/African-AmericanChronic painHIV/AIDSnegative social supportsubstance/drug use

Identifiers

PMID27050708
PMCPMC5002221
OpenAlexW2334316380

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.