Evidence map›Paper›PMID 27050683›Full record

ArticleStructure (London, England : 1993)2016

Exposing the Molecular Machinery of BK Polyomavirus.

Christopher B Buck

Abstract readComment
In one paragraph

Article in Structure (London, England : 1993), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Agnoprotein Is an Essential Egress Factor during BK Polyomavirus Infection.International journal of molecular sciences · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Christopher B BuckCenter for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA. Electronic address: buckc@mail.nih.gov.

Funding

Molecular biology of human polyomavirusesZIABC011090 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BUCK, CHRISTOPHER · 2009 to 2025
$9.3M
BKV and JCV vaccine developmentZIABC011460 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BUCK, CHRISTOPHER · 2012 to 2025
$7.8M
Intramural NIH HHS ZIA BC011460Medical Research Council MR/K012665/1
6 · The paper itself

Abstract

BK polyomavirus (BKV) is an opportunistic pathogen that poses a serious threat to organ transplant recipients. In this issue of Structure, Hurdiss and colleagues' (Hurdiss et al., 2016) beautiful new high-resolution cryo-EM reconstruction of BKV provides a structural roadmap for the ongoing development of therapeutic antibodies and vaccines targeting this potentially deadly virus. The study also serves as a platform for exploring the basic biology of virion assembly and infectious entry.

Indexed as

BK VirusPolyomavirus InfectionsKidney TransplantationModels, Molecular

Identifiers

PMID27050683
PMCPMC6289593

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.