ArticlePloS one2016
Reduced Prefrontal Cortex Hemodynamic Response in Adults with Methamphetamine Induced Psychosis: Relevance for Impulsivity.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Fronto-striatal neurometabolite signatures of impulsivity in early abstinence from methamphetamine.NeuroImage. Clinical · 2026Article
- Abnormal DLPFC activation in severe methamphetamine use disorder during abstinence: fNIRS evidence from Stroop task.Frontiers in psychiatry · 2026Article
- Measurement of Impulsivity and Its Role in Drug Use Behaviours and Related Health, Harm and Treatment Outcomes Among People Who Use Illicit Drugs-A Scoping Review.International journal of mental health and addiction · 2026Article
- Research on drug addiction detection based on AR-TSNET with bimodal EEG-NIRS.Biomedical engineering online · 2025Article
- Reduced prefrontal hemodynamic responses measured using near-infrared spectroscopy in adults with autism spectrum disorder.Frontiers in psychiatry · 2024Article
- Food stimuli decrease activation in regions of the prefrontal cortex related to executive function: an fNIRS study.Eating and weight disorders : EWD · 2023Article
- The predictive role of impulsivity and perceived social support in psychiatric symptoms of women with methamphetamine use disorder.Frontiers in psychiatry · 2023Article
- A 6-Month Follow-Up Study: Cognitive Impairment May Predict More Frequent Use of Methamphetamine.Substance abuse : research and treatment · 2023Article
- Assessing the mediating role of impulsivity between methamphetamine-induced psychotic disorders and increased gambling severity in methamphetamine-dependent individuals.European archives of psychiatry and clinical neuroscience · 2022Article
- Prefrontal fNIRS-based clinical data analysis of brain functions in individuals abusing different types of drugs.Journal of biomedical semantics · 2021Article
- Differential therapeutic effects of atomoxetine and methylphenidate in childhood attention deficit/hyperactivity disorder as measured by near-infrared spectroscopy.Child and adolescent psychiatry and mental health · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with methamphetamine abuse/dependence often exhibit high levels of impulsivity, which may be associated with the structural abnormalities and functional hypoactivities observed in the frontal cortex of these subjects. Although near-infrared spectroscopy (NIRS) is a simple and non-invasive method for characterizing the clinical features of various psychiatric illnesses, few studies have used NIRS to directly investigate the association between prefrontal cortical activity and inhibitory control in patients with methamphetamine-induced psychosis (MAP). Using a 24-channel NIRS system, we compared hemodynamic responses during the Stroop color-word task in 14 patients with MAP and 21 healthy controls matched for age, sex and premorbid IQ. In addition, we used the Barrett Impulsivity Scale-11 (BIS-11) to assess impulsivity between subject groups. The MAP group exhibited significantly less activation in the anterior and frontopolar prefrontal cortex accompanied by lower Stroop color-word task performance, compared with controls. Moreover, BIS-11 scores were significantly higher in the MAP group, and were negatively correlated with the hemodynamic responses in prefrontal cortex. Our data suggest that reduced hemodynamic responses in the prefrontal cortex might reflect higher levels of impulsivity in patients with MAP, providing new insights into disrupted inhibitory control observed in MAP.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.