Evidence map›Paper›PMID 27050351›Full record

ArticleIndian journal of ophthalmology2016

Systematic approach to managing vernal keratoconjunctivitis in clinical practice: Severity grading system and a treatment algorithm.

Nikhil S Gokhale

2 registry-linked trialsOpen access · diamondAbstract read
In one paragraph

Article in Indian journal of ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04695795 unknown statusnot on this mapstarted 2021, after this paper: background citation

Efficacy and Safety of Seawater in Allergic Conjunctivitis. IgE and MMP-9 Tear Levels. Antihistaminic Eyedrops Comparative Study.

TypeobservationalSponsorUniversity of ValenciaRan2021 to 2022Enrolled50ConditionsAllergic Conjunctivitis
NCT07138742 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy and Safety of Tacrolimus Eye Drops in Treatment of Vernal Keratoconjunctivitis

TypeinterventionalSponsorSohag UniversityRan2025 to 2027Enrolled90ConditionsVernal KeratoconjunctivitisArmsSteroid eye drops, Tacrolimus eye drops
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Vernal Keratoconjunctivitis: A Systematic Review.Clinical reviews in allergy & immunology · 2023
    Pooled it
  2. Observational
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  20. Allergic conjunctivitis.Community eye health · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Nikhil S GokhaleGokhale Eye Hospital, Mumbai, Maharashtra, India.
Gokhale Institute of Politics and Economics · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vernal keratoconjunctivitis is an ocular allergy that is common in the pediatric age group. It is often chronic, severe, and nonresponsive to the available treatment options. Management of these children is difficult and often a dilemma for the practitioner. There is a need to simplify and standardize its management. To achieve this goal, we require a grading system to judge the severity of inflammation and an algorithm to select the appropriate medications. This article provides a simple and practically useful grading system and a stepladder algorithm for systematic treatment of these patients. Use of appropriate treatment modalities can reduce treatment and disease-related complications.

Indexed as

AlgorithmsSeverity of Illness IndexConjunctivitis, AllergicCyclosporineDrug CombinationsHumansImmunosuppressive AgentsOphthalmic SolutionsTacrolimusCyclosporineDrug CombinationsImmunosuppressive AgentsOphthalmic SolutionsTacrolimus

Identifiers

PMID27050351
PMCPMC4850811
OpenAlexW2323977050

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.