Evidence map›Paper›PMID 27050266›Full record

ArticleActa crystallographica. Section F, Structural biology communications2016

Applications of thin-film sandwich crystallization platforms.

Danny Axford, Pierre Aller, Juan Sanchez-Weatherby, James Sandy

Abstract read
In one paragraph

Article in Acta crystallographica. Section F, Structural biology communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Microfluidic Devices for High-Throughput In Situ Serial Crystallography.Advances in biochemical engineering/biotechnology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. A fully automated crystallization apparatus for small protein quantities.Acta crystallographica. Section F, Structural biology communications · 2021
    Article
  12. Review
  13. Low-doseIUCrJ · 2020
    Article
  14. Article
  15. High-throughput in situ experimental phasing.Acta crystallographica. Section D, Structural biology · 2020
    Article
  16. 3D-printed holders forJournal of applied crystallography · 2020
    Article
  17. Article
  18. Article
  19. Crystallography on a chip - without the chip: sheet-on-sheet sandwich.Acta crystallographica. Section D, Structural biology · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Danny AxfordDiamond Light Source, Harwell Oxford, Didcot OX11 0DE, England.
Pierre AllerDiamond Light Source, Harwell Oxford, Didcot OX11 0DE, England.
Juan Sanchez-WeatherbyDiamond Light Source, Harwell Oxford, Didcot OX11 0DE, England.
James SandyDiamond Light Source, Harwell Oxford, Didcot OX11 0DE, England.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Examples are shown of protein crystallization in, and data collection from, solutions sandwiched between thin polymer films using vapour-diffusion and batch methods. The crystallization platform is optimal for both visualization and in situ data collection, with the need for traditional harvesting being eliminated. In wells constructed from the thinnest plastic and with a minimum of aqueous liquid, flash-cooling to 100 K is possible without significant ice formation and without any degradation in crystal quality. The approach is simple; it utilizes low-cost consumables but yields high-quality data with minimal sample intervention and, with the very low levels of background X-ray scatter that are observed, is optimal for microcrystals.

Indexed as

CrystallizationCrystallography, X-RayPolymersPolymerscrystallizationcrystal visual inspectiondiffraction data collectionin situ X-ray analysisprotein crystallization devices

Identifiers

PMID27050266
PMCPMC4822989

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.