Evidence map›Paper›PMID 27049779›Full record

ArticleJournal of the American College of Surgeons2016

Inpatient Rehabilitation after Liver Transplantation Decreases Risk and Severity of 30-Day Readmissions.

Anai N Kothari, Ryan M Yau, Robert H Blackwell, Colleen Schaidle-Blackburn, Talar Markossian, Matthew A C Zapf, Amy D Lu, Paul C Kuo

Registry-linked trialAbstract read
In one paragraph

Article in Journal of the American College of Surgeons, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03529656 (The Safety and Efficacy of Early Rehabilitation Program in Immediate Liver Transplant Patients), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03529656 nacompletednot on this map

The Safety and Efficacy of Early Rehabilitation Program in Immediate Liver Transplant Patients

TypeinterventionalSponsorAsan Medical CenterRan2014 to 2017Enrolled236ConditionsICU-acquired WeaknessArmsEarly rehabilitation program for liver transplantation
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Acute Inpatient Rehabilitation Functional Outcomes and Disposition After Liver Transplant.Archives of rehabilitation research and clinical translation · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Potential savings in the treatment pathway of liver transplantation: an inter-sectorial analysis of cost-rising factors.The European journal of health economics : HEPAC : health economics in prevention and care · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Anai N KothariDepartment of Surgery, Loyola University Medical Center, Maywood, IL; One:MAP Analytics Research Group, Loyola University Medical Center, Department of Surgery, Maywood, IL.
Ryan M YauOne:MAP Analytics Research Group, Loyola University Medical Center, Department of Surgery, Maywood, IL.
Robert H BlackwellDepartment of Urology, Loyola University Medical Center, Maywood, IL; One:MAP Analytics Research Group, Loyola University Medical Center, Department of Surgery, Maywood, IL.
Colleen Schaidle-BlackburnDepartment of Surgery, Loyola University Medical Center, Maywood, IL.
Talar MarkossianDepartment of Public Health Sciences, Loyola University Chicago, Chicago, IL.
Matthew A C ZapfDepartment of Surgery, Loyola University Medical Center, Maywood, IL; One:MAP Analytics Research Group, Loyola University Medical Center, Department of Surgery, Maywood, IL.
Amy D LuDepartment of Surgery, Loyola University Medical Center, Maywood, IL; One:MAP Analytics Research Group, Loyola University Medical Center, Department of Surgery, Maywood, IL.
Paul C KuoDepartment of Surgery, Loyola University Medical Center, Maywood, IL; One:MAP Analytics Research Group, Loyola University Medical Center, Department of Surgery, Maywood, IL. Electronic address: paul.kuo@luhs.org.

Funding

TRAINING IN TRAUMA AND BURN RESEARCHT32GM008750 · NIGMS · LOYOLA UNIVERSITY CHICAGO · PI CHOUDHRY, MASHKOOR A, GONZALEZ, RICHARD PAUL · 2000 to 2023
$2.9M
NIGMS NIH HHS T32 GM008750
6 · The paper itself

Abstract

backgroundDischarge location is associated with short-term readmission rates after hospitalization for several medical and surgical diagnoses. We hypothesized that discharge location: home, home health, skilled nursing facility (SNF), long-term acute care (LTAC), or inpatient rehabilitation, independently predicted the risk of 30-day readmission and severity of first readmission after orthotopic liver transplantation. STUDY

designWe performed a retrospective cohort review using Healthcare Cost and Utilization Project (HCUP) State Inpatient Databases for Florida and California. Patients who underwent orthotopic liver transplantation from 2009 to 2011 were included and followed for 1 year. Mixed-effects logistic regression was used to model the effect of discharge location on 30-day readmission controlling for demographic, socioeconomic, and clinical factors. Total cost of first readmission was used as a surrogate measure for readmission severity and resource use.

resultsA total of 3,072 patients met our inclusion criteria. The overall 30-day readmission rate was 29.6%. Discharge to inpatient rehabilitation (adjusted odds ratio [aOR] 0.43, p = 0.013) or LTAC/SNF (aOR 0.63, p = 0.014) were associated with decreased odds of 30-day readmission when compared with home. The severity of 30-day readmissions for patients discharged to inpatient rehabilitation were the same as those discharged home or home with home health. Severity was increased for those discharged to LTAC/SNF. The time to first readmission was longest for patients discharged to inpatient rehabilitation (17 days vs 8 days, p < 0.001).

conclusionsWhen compared with other locations of discharge, inpatient rehabilitation reduces the risk of 30-day readmission and increases the time to first readmission. These benefits come without increasing the severity of readmission. Increased use of inpatient rehabilitation after orthotopic liver transplantation is a strategy to improve 30-day readmission rates.

Indexed as

AdolescentAdultAgedAged, 80 and overDatabases, FactualFemaleFollow-Up StudiesHome Care ServicesHospitalizationHumansLiver TransplantationLong-Term CareMaleMiddle AgedPatient DischargePatient Readmission

Identifiers

PMID27049779
PMCPMC5105886

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.