ReviewAnnual review of analytical chemistry (Palo Alto, Calif.)2016
Advances in Magnetic Resonance Imaging Contrast Agents for Biomarker Detection.
Review in Annual review of analytical chemistry (Palo Alto, Calif.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Overview of Optical Fiber Biosensors for the Detection of Cancer Biomarkers in the Past Decade.ACS omega · 2026Review
- Nitroxide-Based Contrast Agents for MRI Cancer Diagnostics: Progress, Limitations, and Perspectives.Molecules (Basel, Switzerland) · 2026Review
- Recent Advances in Fluorinated Colloidal Nanosystems for Biological Detection and Surface Coating.Polymers · 2026Review
- Hybrid FeInternational journal of molecular sciences · 2026Article
- Rapid in situ carbon-13 hyperpolarization and imaging of acetate and pyruvate esters without external polarizer.Communications chemistry · 2024Article
- Non-radioactive imaging strategies forPhysical sciences reviews · 2023Article
- Increased Sensitivity of Computed Tomography Scan for Neoplastic Tissues Using the Extracellular Vesicle Formulation of the Contrast Agent Iohexol.Pharmaceutics · 2022Article
- Current approaches and advances in the imaging of stroke.Disease models & mechanisms · 2021Review
- Activatable Nanoparticles: Recent Advances in Redox-Sensitive Magnetic Resonance Contrast Agent Candidates Capable of Detecting Inflammation.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Current Perspectives on Clinical Use of Exosomes as a Personalized Contrast Media and Theranostics.Cancers · 2020Review
- Use of imaging to assess the activity of hepatic transporters.Expert opinion on drug metabolism & toxicology · 2020Review
- Iodine quantification and detectability thresholds among major dual-energy CT platforms.The British journal of radiology · 2019Article
- Focus on the glycerophosphocholine pathway in choline phospholipid metabolism of cancer.NMR in biomedicine · 2019Review
- In vivo magnetic resonance imaging and spectroscopy. Technological advances and opportunities for applications continue to abound.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2019Review
- Contrast Agents Delivery: An Up-to-Date Review of Nanodiagnostics in Neuroimaging.Nanomaterials (Basel, Switzerland) · 2019Review
- QuantitativeMagma (New York, N.Y.) · 2019Article
- Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers.Chemical reviews · 2019Review
- TACS applied bio materials · 2018Article
- Methods of Measuring Enzyme Activity Ex Vivo and In Vivo.Annual review of analytical chemistry (Palo Alto, Calif.) · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Recent advances in magnetic resonance imaging (MRI) contrast agents have provided new capabilities for biomarker detection through molecular imaging. MRI contrast agents based on the T2 exchange mechanism have more recently expanded the armamentarium of agents for molecular imaging. Compared with T1 and T2* agents, T2 exchange agents have a slower chemical exchange rate, which improves the ability to design these MRI contrast agents with greater specificity for detecting the intended biomarker. MRI contrast agents that are detected through chemical exchange saturation transfer (CEST) have even slower chemical exchange rates. Another emerging class of MRI contrast agents uses hyperpolarized (13)C to detect the agent with outstanding sensitivity. These hyperpolarized (13)C agents can be used to track metabolism and monitor characteristics of the tissue microenvironment. Together, these various MRI contrast agents provide excellent opportunities to develop molecular imaging for biomarker detection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.