Evidence map›Paper›PMID 27049063›Full record

ArticleMucosal immunology2017

Eosinophils subvert host resistance to an intracellular pathogen by instigating non-protective IL-4 in CCR2

A H Verma, C L Bueter, M E Rothenberg, G S Deepe

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mucosal immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

A H VermaDivision of Immunobiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA.
C L BueterDivision of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
M E RothenbergDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA.
G S DeepeDivision of Infectious Diseases, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
University of Cincinnati Medical Center · USUniversity of Cincinnati · US

Funding

Pulmonary Development and Disease Pathogenesis Training ProgramT32HL007752 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI Francis Xavier McCormack, Anne-Karina Theresia Perl · 1994 to 2026
$6.3M
GM-CSF-Induced Metal Sequestration and HistoplasmaR01AI106269 · NIAID · UNIVERSITY OF CINCINNATI · PI DEEPE, GEORGE S. · 2013 to 2022
$5.0M
REGULATION OF GASTROINTESTINAL EOSINOPHILSR01AI045898 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 1999 to 2024
$4.5M
Regulation of Gastrointestinal EosinophilsR37AI045898 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI ROTHENBERG, MARC E. · 2010 to 2019
$3.6M
Chemokine-Cytokine Nexus in Fungal ImmunityR01AI083313 · NIAID · UNIVERSITY OF CINCINNATI · PI DEEPE, GEORGE S. · 2010 to 2014
$1.9M
Chemokine-Cytokine Nexus in Fungal ImmunityR56AI083313 · NIAID · UNIVERSITY OF CINCINNATI · PI DEEPE, GEORGE S. · 2009 to 2009
$294k
Molecular and Cellular Determinants of Immunity to HistoplasmosisI01BX000717 · VA · CINCINNATI VA MEDICAL CENTER RESEARCH · PI DEEPE, GEORGE S. · 2011 to 2017
–
BLRD VA I01 BX000717NHLBI NIH HHS T32 HL007752NIAID NIH HHS R01 AI045898NIAID NIH HHS R01 AI083313NIAID NIH HHS R01 AI106269NIAID NIH HHS R37 AI045898NIAID NIH HHS R56 AI083313
6 · The paper itself

Abstract

Eosinophils contribute to type II immune responses in helminth infections and allergic diseases; however, their influence on intracellular pathogens is less clear. We previously reported that CCR2

Indexed as

AnimalsAntigens, FungalCells, CulturedEosinophilsHistoplasmaHistoplasmosisHumansImmune EvasionImmunity, InnateInterleukin-4Macrophage-1 AntigenMaleMiceMice, Inbred C57BLMice, KnockoutPhagocytosisAntigens, FungalCcr2 protein, mouseInterleukin-4Macrophage-1 AntigenReceptors, CCR2

Identifiers

PMID27049063
PMCPMC5053824
OpenAlexW2334948713

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.