Evidence map›Paper›PMID 27049059›Full record

ArticleMucosal immunology2017

Macrophage migration inhibitory factor deficiency enhances immune response to Nippostrongylus brasiliensis.

Sheela R Damle, Rebecca K Martin, Janet V Cross, Daniel H Conrad

Open access · bronzeAbstract read
In one paragraph

Article in Mucosal immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Modulation of the Immune Response by Nematode Derived Molecules.International journal of molecular sciences · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. The Role of MIF on Eosinophil Biology and Eosinophilic Inflammation.Clinical reviews in allergy & immunology · 2020
    Review
  8. TheJournal of immunology (Baltimore, Md. : 1950) · 2019
    Article
  9. Article
  10. Expression of macrophage migration inhibitory factor inInternational journal of ophthalmology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sheela R Damle *Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA 23298.
Rebecca K Martin *Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA 23298.
Janet V CrossDepartment of Pathology, University of Virginia, Charlottesville, VA 22904.
Daniel H ConradDepartment of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA 23298.
Virginia Commonwealth University · USUniversity of Virginia · US

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Keri R Maher · 1985 to 2026
$51.0M
Virginia Commonwealth University IRADCAK12GM093857 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI DANIEL C BULLARD, John J Ryan · 2010 to 2026
$7.0M
STRUCTURE/FUNCTION OF THE LYMPHOCYTE FCE RECEPTORR01AI018697 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI MARTIN, REBECCA KELLEY · 1985 to 2018
$6.5M
VCU Neuroscience Center Core GrantP30NS047463 · NINDS · VIRGINIA COMMONWEALTH UNIVERSITY · PI POVLISHOCK, JOHN T · 2003 to 2013
$5.0M
Mast cell mediators augment the immunoregulatory function of MDSCs.F30CA192836 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI DAMLE, SHEELA RUBY · 2015 to 2018
$169k
NCI NIH HHS F30 CA192836NCI NIH HHS P30 CA016059NIAID NIH HHS R01 AI018697NIGMS NIH HHS K12 GM093857NINDS NIH HHS P30 NS047463
6 · The paper itself

Abstract

Infections with helminth parasites are endemic in the developing world and are a target for intervention with new therapies. Macrophage migration inhibitory factor (MIF) is a cytokine with pleiotropic effects in inflammation and immune responses. We investigated the role of MIF in a naturally cleared model of helminth infection in rodents, Nippostrongylus brasiliensis. At day 7 postinfection, MIF-deficient (MIF

Indexed as

AnimalsAntigens, HelminthCells, CulturedFemaleGATA3 Transcription FactorImmunityInterleukin-13Intramolecular OxidoreductasesIsothiocyanatesMacrophage Migration-Inhibitory FactorsMacrophagesMaleMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutAntigens, Helminthdopachrome isomeraseGata3 protein, mouseGATA3 Transcription FactorInterleukin-13Intramolecular OxidoreductasesIsothiocyanatesMacrophage Migration-Inhibitory FactorsMif protein, mousesulforaphaneSulfoxides

Identifiers

PMID27049059
PMCPMC5053838
OpenAlexW2332759606

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.