Evidence map›Paper›PMID 27048658›Full record

ArticleJournal of neurogastroenterology and motility2016

Per Oral Endoscopic Myotomy in Children with Achalasia Cardia.

Zaheer Nabi, Mohan Ramchandani, D Nageshwar Reddy, Santosh Darisetty, Rama Kotla, Rakesh Kalapala, Radhika Chavan

Open access · diamondAbstract read
In one paragraph

Article in Journal of neurogastroenterology and motility, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. POEM in the Treatment of Esophageal Disorders.Current treatment options in gastroenterology · 2018
    Review
  10. Review
  11. Review
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zaheer NabiDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, India.
Mohan RamchandaniDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, India.
D Nageshwar ReddyDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, India.
Santosh DarisettyDepartment of Anesthesiology, Asian Institute of Gastroenterology, Hyderabad, India.
Rama KotlaDepartment of Anesthesiology, Asian Institute of Gastroenterology, Hyderabad, India.
Rakesh KalapalaDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, India.
Radhika ChavanDepartment of Gastroenterology, Asian Institute of Gastroenterology, Hyderabad, India.
Asian Institute of Gastroenterology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsAchalasia cardia (AC) is a motility disorder, characterized by impaired lower esophageal sphincter relaxation and absence of esophageal peristalsis. AC is rare in children with unclear optimum management strategies. Per oral endoscopic myotomy (POEM) is a novel technique for management of achalasia with encouraging results in adult patients. The efficacy and safety of POEM is not known for pediatric AC. The aim of our study was to evaluate the safety and efficacy of POEM in children with achalasia cardia.

methodsThe data of all children (< 18 years) who underwent POEM at our center was retrospectively analysed. Symptoms were analysed using a validated score (Eckardt score) at regular predefined intervals. Objective parameters including high-resolution manometry, timed barium swallow and esophagogastroduodenoscopy were assessed before the procedure and at 1-year follow-up. Clinical success was defined as an Eckardt score ≤ 3.

resultsA total of 15 children underwent POEM during the specified period. Ten out of 15 (10/15) completed 1-year follow-up. Median operative time was 100 (38-240) minutes. Mean pre and post procedure LES pressure were 36.64 ± 11.08 mmHg and 15.65 ± 5.73 mmHg, respectively (

conclusionsPOEM is safe and effective for children and adolescents with achalasia. Future trials with larger sample size are warranted to establish its efficacy in pediatric AC.

Indexed as

Achalasia cardiaChildEndoscopic surgical procedure

Identifiers

PMID27048658
PMCPMC5056570
OpenAlexW2316323368

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.