ArticleCritical care (London, England)2016
How ARDS should be treated.
Article in Critical care (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 44 citations in OpenAlex.
- Effect of driving pressure on mortality in ARDS patients during lung protective mechanical ventilation in two randomized controlled trials.Critical care (London, England) · 2016Trial
- Low PEEP ventilation in TGF-β1 induced lung injury triggers a reversible lung mechanical deterioration without promoting persistent structural damage.Scientific reports · 2026Article
- The Impact of Mechanical Energy Assessment on Mechanical Ventilation: A Comprehensive Review and Practical Application.Medical science monitor : international medical journal of experimental and clinical research · 2023Review
- A framework for heart-lung interaction and its application to prone position in the acute respiratory distress syndrome.Frontiers in physiology · 2023Article
- Acute respiratory failure on varicella pneumonia in Indonesian adult with chronic hepatitis B: A case report and review article.Annals of medicine and surgery (2012) · 2022Article
- Biomarkers of Cholestasis and Liver Injury in the Early Phase of Acute Respiratory Distress Syndrome and Their Pathophysiological Value.Diagnostics (Basel, Switzerland) · 2021Article
- Effect of N-Acetylcysteine on the treatment of acute respiratory distress syndrome in mechanically ventilated patients admitted to the intensive care unit.Medical journal of the Islamic Republic of Iran · 2021Article
- Effect of mechanical power on intensive care mortality in ARDS patients.Critical care (London, England) · 2020Article
- Unfolded Protein Response supports endothelial barrier function.Biochimie · 2019Review
- The Effect of Positive End-Expiratory Pressure on Lung Micromechanics Assessed by Synchrotron Radiation Computed Tomography in an Animal Model of ARDS.Journal of clinical medicine · 2019Article
- Ventilation-induced lung injury exists in spontaneously breathing patients with acute respiratory failure: We are not sure.Intensive care medicine · 2017Article
- Correlation between nitric oxide content in exhaled breath condensate and the severity of acute respiratory distress syndrome.International journal of clinical and experimental pathology · 2017Article
- Computational design and experimental analysis of a novel visor for COVID-19 patients receiving high-flow nasal oxygen therapy.European journal of mechanics. B, FluidsArticle
- Acute exacerbations of idiopathic pulmonary fibrosis: Does clinical stratification or steroid treatment matter?Chronic respiratory diseaseObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Berlin definition criteria applied at positive end-expiratory pressure (PEEP) 5 cm H2O reasonably predict lung edema and recruitabilty. To maintain viable gas exchange, the mechanical ventilation becomes progressively more risky going from mild to severe acute respiratory distress syndrome (ARDS). Tidal volume, driving pressure, flow, and respiratory rate have been identified as causes of ventilation-induced lung injury. Taken together, they represent the mechanical power applied to the lung parenchyma. In an inhomogeneous lung, stress risers locally increase the applied mechanical power. Increasing lung homogeneity by PEEP and prone position decreases the harm of mechanical ventilation, particularly in severe ARDS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.