Evidence map›Paper›PMID 27048473›Full record

ReviewCurrent osteoporosis reports2016

Advances in Nanotechnology for the Treatment of Osteoporosis.

Mikayla Barry, Hannah Pearce, Lauren Cross, Marco Tatullo, Akhilesh K Gaharwar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current osteoporosis reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 96 citations in OpenAlex.

  1. Consequences of Aging on Bone.Aging and disease · 2023
    Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. In and outside the spotlight: Nanomedicine in the treatment of osteoporosis.The Journal of international medical research · 2025
    Review
  8. Article
  9. Review
  10. Osteoporosis therapy using nanoparticles: a review.Annals of medicine and surgery (2012) · 2024
    Review
  11. Article
  12. Review
  13. Age of the donor affects the nature ofThe Saudi dental journal · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Blockchain in Healthcare: Insights on COVID-19.International journal of environmental research and public health · 2020
    Article
  18. Organoids in Translational Oncology.Journal of clinical medicine · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mikayla BarryDepartment of Biomedical Engineering, Texas A&M University, College Station, TX, 77841, USA.
Hannah PearceDepartment of Biomedical Engineering, Texas A&M University, College Station, TX, 77841, USA.
Lauren CrossDepartment of Biomedical Engineering, Texas A&M University, College Station, TX, 77841, USA.
Marco TatulloMaxillofacial Unit, Calabrodental Clinic, Crotone, 88900, Italy.
Akhilesh K GaharwarDepartment of Biomedical Engineering, Texas A&M University, College Station, TX, 77841, USA. gaharwar@tamu.edu.
Texas A&M University · USIstituto S.Anna Crotone · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis is a degenerative bone disease commonly related to aging. With an increase in life expectancies worldwide, the prevalence of the disease is expected to rise. Current clinical therapeutic treatments are not able to offer long-term solutions to counter the bone mass loss and the increased risk of fractures, which are the primary characteristics of the disease. However, the combination of bioactive nanomaterials within a biomaterial scaffold shows promise for the development of a localized, long-term treatment for those affected by osteoporosis. This review summarizes the unique characteristics of engineered nanoparticles that render them applicable for bone regeneration and recaps the current body of knowledge on nanomaterials with potential for osteoporosis treatment and bone regeneration. Specifically, we highlight new developments that are shaping this emerging field and evaluate applications of recently developed nanomaterials for osteoporosis treatment. Finally, we will identify promising new research directions in nanotechnology for bone regeneration.

Indexed as

Bone RegenerationBiocompatible MaterialsBone DensityBone Morphogenetic Protein 2Bone RemodelingDrug Delivery SystemsEstrogensFractures, BoneHumansNanostructuresNanotechnologyOsteoporosisTissue EngineeringBiocompatible MaterialsBone Morphogenetic Protein 2EstrogensBioactive nanomaterialsBone regenerationNanotechnologyOsteoporosis

Identifiers

PMID27048473
OpenAlexW2335640937

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.