Evidence map›Paper›PMID 27048450›Full record

ArticleDigestive diseases and sciences2016

Hearing Loss in Patients with Inflammatory Bowel Disease.

Dov Wengrower, Benjamin Koslowsky, Uri Peleg, Betty Mazuz, Leore Cohen, Allin Ben-David, Menahem Gross, Eran Goldin, Chanan Shaul

Abstract read
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In one paragraph

Article in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Is routine hearing screening necessary in patients with inflammatory bowel disease - a prospective study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  7. Article
  8. A High-Fat Diet Induces Low-Grade Cochlear Inflammation in CD-1 Mice.International journal of molecular sciences · 2022
    Article
  9. Sensorineural hearing loss and ulcerative colitis in remission.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2022
    Observational
  10. The Link between Gut Dysbiosis Caused by a High-Fat Diet and Hearing Loss.International journal of molecular sciences · 2021
    Review
  11. Assessment of Hearing Function in Children with Inflammatory Bowel Disease.The journal of international advanced otology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Dov WengrowerDigestive Diseases Institute, Shaare Zedek Medical Center, Hebrew University Medical School, 12 Bayit St., 91031, Jerusalem, Israel.
Benjamin KoslowskyDigestive Diseases Institute, Shaare Zedek Medical Center, Hebrew University Medical School, 12 Bayit St., 91031, Jerusalem, Israel. binyaminkos@szmc.org.il.ORCID 0000-0002-6935-6051
Uri PelegDepartment of Otolaryngology Head and Neck Surgery, Shaare Zedek Medical Center, Jerusalem, Israel.
Betty MazuzDigestive Diseases Institute, Shaare Zedek Medical Center, Hebrew University Medical School, 12 Bayit St., 91031, Jerusalem, Israel.
Leore CohenDepartment of Otolaryngology Head and Neck Surgery, Hadassah University Hospital, Jerusalem, Israel.
Allin Ben-DavidDepartment of Gastroenterolgy, Hadassah University Hospital, Jerusalem, Israel.
Menahem GrossDepartment of Otolaryngology Head and Neck Surgery, Hadassah University Hospital, Jerusalem, Israel.
Eran GoldinDigestive Diseases Institute, Shaare Zedek Medical Center, Hebrew University Medical School, 12 Bayit St., 91031, Jerusalem, Israel.
Chanan ShaulDepartment of Otolaryngology Head and Neck Surgery, Shaare Zedek Medical Center, Jerusalem, Israel.
Shaare Zedek Medical Center · ILHadassah Academic College · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsInflammatory bowel disease (IBD) has many characteristics of autoimmune diseases. Sensorineural hearing loss has been reported in many autoimmune diseases. Little is known about hearing loss in patients with IBD.

methodsA prospective blinded comparative study was conducted over a 3-year period. IBD patients and controls underwent a complete otorhinolaryngeal examination and eudiometry test.

resultsAltogether 105 participants (76 patients and 29 controls) took part in this study. Mean age was 36, 51 % were males, and 40 % of the patients were presently hospitalized due to IBD exacerbation. Audiometric examination revealed that any hearing loss (mild to severe) was found in 29 (38 %) of the IBD population, compared to 4 (14 %) of the control group (p = 0.02). Extraintestinal manifestation (EIM) was present in 33/76 (43 %) of IBD patients. Any hearing loss and moderate to severe hearing loss were found in 17/33 (52 %) and 7/33 (21 %) in the EIM-positive group compared to 12/43 (28 %) and 4/43 (9 %) in the EIM-negative group (p = 0.036 and p = 0.14, respectively). Out of patients over the age of 40 with other EIMs, all 11/11 (100 %) of patients had any hearing loss compared to 8/12 (66 %) of patients over the age of 40 without other EIMs, p = 0.035.

conclusionsHearing loss may be another EIM of IBD. It is found in 38 % of IBD patients and in up to 52 % of patients with other EIMs and increases over the age of 40. Early hearing evaluation should be recommended to these high-risk IBD patients.

Indexed as

AdultAgedCase-Control StudiesFemaleHearing LossHumansInflammatory Bowel DiseasesMaleMiddle AgedProspective StudiesYoung AdultAudiometric examinationExtraintestinal manifestationsHearing lossInflammatory bowel disease

Identifiers

PMID27048450
OpenAlexW2321469699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.