ArticleInfection2016
Statins and Aspirin use in HIV-infected people: gap between European AIDS Clinical Society guidelines and clinical practice: the results from HIV-HY study.
Article in Infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 54 citations in OpenAlex.
- Risk Assessment in a Global CVD Prevention Cohort of People With HIV by PCE, PREVENT, and SCORE2.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- Use of Preventive Measures for Cardiovascular Disease in People With HIV.Open forum infectious diseases · 2025Article
- Prevalence of Cardiovascular Disease and Comparison of Risk Category Predictions of Systemic Coronary Risk Evaluation Score-2 and 4 Other Cardiovascular Disease Risk Assessment Tools Among People Living with Human Immunodefficiency Virus in Türkiye.Anatolian journal of cardiology · 2024Article
- Atherosclerosis and Cardiovascular Complications in People Living with HIV: A Focused Review.Infectious disease reports · 2024Review
- For which HIV Patients Aspirin and Statins are Good?Arquivos brasileiros de cardiologia · 2021Article
- Evolution of comorbidities in people living with HIV between 2004 and 2014: cross-sectional analyses from ANRS CO3 Aquitaine cohort.BMC infectious diseases · 2020Article
- Smoking habits in HIV-infected people compared with the general population in Italy: a cross-sectional study.BMC public health · 2020Article
- Cholesterol-lowering effect of statin therapy in a clinical HIV cohort: an application of double propensity score adjustment.Annals of epidemiology · 2020Observational
- Clusterization of co-morbidities and multi-morbidities among persons living with HIV: a cross-sectional study.BMC infectious diseases · 2019Article
- Statins and aspirin in the prevention of cardiovascular disease among HIV-positive patients between controversies and unmet needs: review of the literature and suggestions for a friendly use.AIDS research and therapy · 2019Review
- Older HIV-infected adults: complex patients-comorbidity (I).European geriatric medicine · 2019Article
- Impact of the American College of Cardiology/American Heart Association Cholesterol Guidelines on Statin Eligibility Among Human Immunodeficiency Virus-Infected Individuals.Open forum infectious diseases · 2018Article
- Improvement of lipid profile after switching from efavirenz or ritonavir-boosted protease inhibitors to rilpivirine or once-daily integrase inhibitors: results from a large observational cohort study (SCOLTA).BMC infectious diseases · 2018Observational
- Benefits and Risks of Statin Therapy in the HIV-Infected Population.Current infectious disease reports · 2018Review
- Impact of comorbidity on the risk and cost of hospitalization in HIV-infected patients: real-world data from Abruzzo Region.ClinicoEconomics and outcomes research : CEOR · 2018Article
- Epidemiology of ischemic heart disease in HIV.Current opinion in HIV and AIDS · 2017Review
- Suboptimal primary and secondary cardiovascular disease prevention in HIV-positive individuals on antiretroviral therapy.European journal of preventive cardiology · 2017Article
- Observed versus predicted cardiovascular events and all-cause death in HIV infection: a longitudinal cohort study.BMC infectious diseases · 2017Article
- Cardiovascular disease risk among Chinese antiretroviral-naïve adults with advanced HIV disease.BMC infectious diseases · 2017Article
- Pre-clinical carotid atherosclerosis and sCD163 among virally suppressed HIV patients in Botswana compared with uninfected controls.PloS one · 2017Article
Corrections and comments
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Authors and funding
15 authors at 14 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the use of statins and acetylsalicylic acid (ASA) in HIV people in clinical practice.
designA multicenter, nationwide, prospective cohort study, including 1182 consecutive HIV patients was conducted.
methodsStatin and ASA prescription was evaluated in primary and secondary cardiovascular disease prevention, according to the European AIDS Clinical Society (EACS) guidelines.
resultsFollowed-up patients (998) were mostly males (70.9 %) with a mean age at enrolment of 46.5 years (SD 9.5). The mean time of follow-up was 3.3 years (SD 0.8). At the last follow-up visit, statins would have been recommended for 31.2 % and ASA for 16 % by EACS guidelines. Conversely, only 15.6 and 7.6 % of patients were on statin and ASA treatment, respectively; only 50.3 % of patients treated with statins achieved recommended low-density lipoprotein cholesterol (LDL-c) levels. At the last follow-up visit, agreement between statin therapy and EACS recommendation was 0.58 (95 % CI 0.52-0.63). The corresponding figure for ASA therapy was 0.50 (95 % CI 0.42-0.58), whereas the agreement for ASA therapy in secondary prevention was 0.59 (95 % CI 0.50-0.68).
conclusionsThe prescription of statins and ASA in HIV-infected patients remains largely suboptimal, as only about 50 % of patients requiring statins and ASA are properly treated. Higher attention on this relevant issue and further investigation are warranted in this at risk population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.