Evidence map›Paper›PMID 27047992›Full record

ArticleBiochemistry and biophysics reports2016

Rapid identification of ubiquitination and SUMOylation target sites by microfluidic peptide array.

Bing Zhu, Tierra R Farris, Sarah L Milligan, Haosi Chen, Ruijuan Zhu, Aailing Hong, Xiaochuan Zhou, Xiaolian Gao, Jere W McBride

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Frontiers in immunology · 2021
    Review
  2. Article
  3. mSphere · 2018
    Article
  4. Article
  5. Frontiers in cellular and infection microbiology · 2017
    Article
  6. Frontiers in cellular and infection microbiology · 2017
    Article
  7. Review
  8. Frontiers in cellular and infection microbiology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Bing ZhuDepartments of Pathology University of Texas Medical Branch, Galveston, TX.
Tierra R FarrisDepartments of Microbiology & Immunology University of Texas Medical Branch, Galveston, TX.
Sarah L MilliganDepartments of Pathology University of Texas Medical Branch, Galveston, TX.
Haosi ChenDepartment of Biology and Biochemistry, University of Houston, TX.
Ruijuan ZhuDepartment of Biology and Biochemistry, University of Houston, TX.
Aailing HongLC Sciences, Houston, TX.
Xiaochuan ZhouLC Sciences, Houston, TX.
Xiaolian GaoDepartment of Biology and Biochemistry, University of Houston, TX.
Jere W McBrideDepartments of Pathology University of Texas Medical Branch, Galveston, TX; Departments of Microbiology & Immunology University of Texas Medical Branch, Galveston, TX; Center for Biodefense and Emerging Infectious Diseases University of Texas Medical Branch, Galveston, TX; Sealy Center for Vaccine Development University of Texas Medical Branch, Galveston, TX; Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX.
The University of Texas Medical Branch at Galveston · USUniversity of Houston · USLone Star College · US

Funding

Ehrlichia T1S Effector Regulation of Host Gene TranscriptionR01AI106859 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI MCBRIDE, JERE W · 2014 to 2017
$1.5M
Ehrlichia Type-1 Secreted Effectors Exploit Host SUMO PathwaysR21AI105536 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI MCBRIDE, JERE W · 2013 to 2014
$421k
NIAID NIH HHS R01 AI106859NIAID NIH HHS R21 AI105536
6 · The paper itself

Abstract

SUMOylation and ubiquitination are two essential post translational modifications (PTMs) involved in the regulation of important biological processes in eukaryotic cells. Identification of ubiquitin (Ub) and small ubiquitin-related modifier (SUMO)-conjugated lysine residues in proteins is critical for understanding the role of ubiquitination and SUMOylation, but remains experimentally challenging. We have developed a powerful

Indexed as

effectorEhrlichiahigh density peptide arraySUMOubiquitin

Identifiers

PMID27047992
PMCPMC4817105
OpenAlexW2259139696

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.