Evidence map›Paper›PMID 27047811›Full record

ArticleJournal of nephropathology2016

Distal, intermediate, and proximal mediators of racial disparities in renal disease mortality in the United States.

Shervin Assari

Registry-linked trialAbstract read
In one paragraph

Article in Journal of nephropathology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03832166 (A Prospective, Randomized Two Group Study to Evaluate the Feasibility and Initial Efficacy of a Community-engaged Screening, Identification, and F&V Intervention to Improve F&V Intake and CKD Outcomes in 140 AA Adults), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03832166 nacompletednot on this mapstarted 2019, after this paper: background citation

A Prospective, Randomized Two Group Study to Evaluate the Feasibility and Initial Efficacy of a Community-engaged Screening, Identification, and F&V Intervention to Improve F&V Intake and CKD Outcomes in 140 AA Adults

TypeinterventionalSponsorBaylor Research InstituteRan2019 to 2020Enrolled142ConditionsCKD, ESRDArmsFruits and Vegetables, Cooking
3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  12. Understanding America: Unequal Economic Returns of Years of Schooling in Whites and Blacks.World journal of educational research (Los Angeles, Calif.) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Shervin AssariDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA ; Center for Research on Ethnicity, Culture and Health, School of Public Health, University of Michigan, Ann Arbor, MI, USA.

Funding

UNDERSTANDING SOCIAL DISPARITIES IN HEALTH AND AGINGR01AG018418 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BURGARD, SARAH A. · 2000 to 2015
$6.3M
NIA NIH HHS R01 AG018418
6 · The paper itself

Abstract

backgroundKidney failure and associated mortality is one of the major components of racial disparities in the United States.

objectivesThe current study aimed to investigate the role of distal (socioeconomic status, SES), intermediate (chronic medical diseases), and proximal (health behaviors) factors that may explain Black-White disparities in mortality due to renal diseases. PATIENTS AND

methodsThis is a nationally representative prospective cohort with 25 years of follow up. Data came from the Americans' Changing Lives (ACL) study, 1986 to 2011. The study included 3361 Black (n = 1156) or White (n = 2205) adults who were followed for up to 25 years. Race was the main predictor and death due to renal disease was the outcome. SES, chronic medical disease (diabetes, hypertension, obesity), and health behaviors (smoking, drinking, and exercise) at baseline were potential mediators. We used Cox proportional hazards models for data analysis.

resultsIn age and gender adjusted models, Blacks had higher risk of death due to renal disease over the follow up period. Separate models suggested that SES, health behaviors and chronic medical disease fully explained the effect of race on renal disease mortality.

conclusionsBlack-White disparities in rate of death due to renal diseases in the United States are not genuine but secondary to racial differences in income, health behaviors, hypertension, and diabetes. As distal, intermediate, and proximal factors contribute to racial disparities in renal disease mortality, elimination of such disparities requires a wide range of policies and programs that target income, medical conditions, and health behaviors.

Indexed as

African AmericansDiabetesEthnic groupsHypertensionMortalityObesityRenal diseasesSocioeconomic status

Identifiers

PMID27047811
PMCPMC4790188

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.