Evidence map›Paper›PMID 27047789›Full record

ReviewGland surgery2016

Adipose regeneration and implications for breast reconstruction: update and the future.

Emman J Combellack, Zita M Jessop, Naghmeh Naderi, Michelle Griffin, Thomas Dobbs, Amel Ibrahim, Stephen Evans, Stephanie Burnell, Shareen H Doak, Iain S Whitaker

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Gland surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Review
  3. Advanced Hydrogels in Breast Cancer Therapy.Gels (Basel, Switzerland) · 2024
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emman J Combellack1 Reconstructive Surgery and Regenerative Medicine Research Group, Institute of Life Science, Swansea University, Swansea, UK ; 2 Burns & Plastic Surgery Department, Morriston Hospital, Swansea, UK ; 3 UCL Centre for Nanotechnology and Regenerative Medicine, University College London, London, UK.
Zita M Jessop1 Reconstructive Surgery and Regenerative Medicine Research Group, Institute of Life Science, Swansea University, Swansea, UK ; 2 Burns & Plastic Surgery Department, Morriston Hospital, Swansea, UK ; 3 UCL Centre for Nanotechnology and Regenerative Medicine, University College London, London, UK.
Naghmeh Naderi1 Reconstructive Surgery and Regenerative Medicine Research Group, Institute of Life Science, Swansea University, Swansea, UK ; 2 Burns & Plastic Surgery Department, Morriston Hospital, Swansea, UK ; 3 UCL Centre for Nanotechnology and Regenerative Medicine, University College London, London, UK.
Michelle Griffin1 Reconstructive Surgery and Regenerative Medicine Research Group, Institute of Life Science, Swansea University, Swansea, UK ; 2 Burns & Plastic Surgery Department, Morriston Hospital, Swansea, UK ; 3 UCL Centre for Nanotechnology and Regenerative Medicine, University College London, London, UK.
Thomas Dobbs1 Reconstructive Surgery and Regenerative Medicine Research Group, Institute of Life Science, Swansea University, Swansea, UK ; 2 Burns & Plastic Surgery Department, Morriston Hospital, Swansea, UK ; 3 UCL Centre for Nanotechnology and Regenerative Medicine, University College London, London, UK.
Amel Ibrahim1 Reconstructive Surgery and Regenerative Medicine Research Group, Institute of Life Science, Swansea University, Swansea, UK ; 2 Burns & Plastic Surgery Department, Morriston Hospital, Swansea, UK ; 3 UCL Centre for Nanotechnology and Regenerative Medicine, University College London, London, UK.
Stephen Evans1 Reconstructive Surgery and Regenerative Medicine Research Group, Institute of Life Science, Swansea University, Swansea, UK ; 2 Burns & Plastic Surgery Department, Morriston Hospital, Swansea, UK ; 3 UCL Centre for Nanotechnology and Regenerative Medicine, University College London, London, UK.
Stephanie Burnell1 Reconstructive Surgery and Regenerative Medicine Research Group, Institute of Life Science, Swansea University, Swansea, UK ; 2 Burns & Plastic Surgery Department, Morriston Hospital, Swansea, UK ; 3 UCL Centre for Nanotechnology and Regenerative Medicine, University College London, London, UK.
Shareen H Doak1 Reconstructive Surgery and Regenerative Medicine Research Group, Institute of Life Science, Swansea University, Swansea, UK ; 2 Burns & Plastic Surgery Department, Morriston Hospital, Swansea, UK ; 3 UCL Centre for Nanotechnology and Regenerative Medicine, University College London, London, UK.
Iain S Whitaker1 Reconstructive Surgery and Regenerative Medicine Research Group, Institute of Life Science, Swansea University, Swansea, UK ; 2 Burns & Plastic Surgery Department, Morriston Hospital, Swansea, UK ; 3 UCL Centre for Nanotechnology and Regenerative Medicine, University College London, London, UK.

Funding

Medical Research Council MR/N002431/1
6 · The paper itself

Abstract

The evolution of breast reconstruction and management of breast cancer has evolved significantly since the earliest descriptions in the Edwin Smith Papyrus (3,000 BC). The development of surgical and scientific expertise has changed the way that women are managed, and plastic surgeons are now able to offer a wide range of reconstructive options to suit individual needs. Beyond the gold standard autologous flap based reconstructions, regenerative therapies promise the elimination of donor site morbidity whilst providing equivalent aesthetic and functional outcomes. Future research aims to address questions regarding ideal cell source, optimisation of scaffold composition and interaction of de novo adipose tissue in the microenvironment of breast cancer.

Indexed as

adiposeAdipose derived stem cell (ADSC)breast reconstructionregenerative medicine

Identifiers

PMID27047789
PMCPMC4791352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.