ArticleApplied & translational genomics2016
An old problem in a new age: Revisiting the clinical dilemma of misattributed paternity.
Article in Applied & translational genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Integrating Genetic Information into the Electronic Health Record: The Case of Adolescents' Revelation of Misattributed Parentage.Journal of bioethical inquiry · 2026Article
- Unmet Health Care Needs of Adult Patients Adopted in Childhood: Insights and Recommendations.Annals of family medicine · 2025Article
- Use of Prenatal Exome Sequencing: Opinion Statement of the French Federation of Human Genetics Working Group.Prenatal diagnosis · 2025Review
- Article
- Genetic and metabolic investigations for neurodevelopmental disorders: position statement of the Canadian College of Medical Geneticists (CCMG).Journal of medical genetics · 2023Article
- Family secrets: Experiences and outcomes of participating in direct-to-consumer genetic relative-finder services.American journal of human genetics · 2022Article
- Genetic Testing in Neurodevelopmental Disorders.Frontiers in pediatrics · 2021Review
- Massively Parallel Sequencing for Rare Genetic Disorders: Potential and Pitfalls.Frontiers in endocrinology · 2020Review
- The ethics and logistics of field-based genetic paternity studies.Evolutionary human sciences · 2020Article
- Prenatal Diagnosis of Cystic Fibrosis and Hemophilia: Incidental Findings and Weak Points.Diagnostics (Basel, Switzerland) · 2019Article
- When genomic medicine reveals misattributed genetic relationships-the debate about disclosure revisited.Genetics in medicine : official journal of the American College of Medical Genetics · 2019Article
- Paediatric genomics: diagnosing rare disease in children.Nature reviews. Genetics · 2018Review
- Opening Pandora's box?: ethical issues in prenatal whole genome and exome sequencing.Prenatal diagnosis · 2018Review
- Ancestry Testing and the Practice of Genetic Counseling.Journal of genetic counseling · 2017Review
- Personal genomics: Where are we now?Applied & translational genomics · 2016Article
- How should we deal with misattributed paternity? A survey of lay public attitudes.AJOB empirical bioethicsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clinical genetics has wrestled with the problem of misattributed paternity for decades. While there are no clear directives on policy, surveys suggest that genetics professionals are inclined to avoid disclosure when possible. Changes associated with the increased use of genomic testing will alter the context and may limit the benefits of non-disclosure. Multi-site testing will preclude the uncertainty often associated with single-gene testing. Increased use of genetic testing in clinical and non-clinical settings will create new opportunities for the subsequent unmasking of misattributed relationships, as will the presence of test results in the electronic medical record. Family health history information will become more valuable as it is used more often and to better effect in risk assessment, diagnosis, treatment and reproductive decision-making. These changes associated with genomic testing increase the risks and decrease the benefits associated with the nondisclosure of misattributed paternity. For ethical and practical reasons, genetics professionals, and those who advise them, should consider a greater emphasis on the value of carefully planned disclosure.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.