Evidence map›Paper›PMID 27047754›Full record

ArticleApplied & translational genomics2016

Attitudes towards personal genomics among older Swiss adults: An exploratory study.

Laura Mählmann, Christina Röcke, Angela Brand, Ernst Hafen, Effy Vayena

Abstract read
In one paragraph

Article in Applied & translational genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Age and perceived risks and benefits of preventive genomic screening.Genetics in medicine : official journal of the American College of Medical Genetics · 2018
    Article
  11. Article
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  13. Personal genomics: Where are we now?Applied & translational genomics · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laura MählmannInstitute of Molecular Systems Biology, ETH Zurich, Auguste-Piccard-Hof 1, 8093 Zürich, Switzerland; Institute for Public Health Genomics, Faculty of Health, Medicine and Life Sciences, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands.
Christina RöckeUniversity Research Priority Program "Dynamics of Healthy Aging", University of Zurich, Andreasstrasse 15/Box 2, 8050 Zurich, Switzerland.
Angela BrandInstitute for Public Health Genomics, Faculty of Health, Medicine and Life Sciences, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands.
Ernst HafenInstitute of Molecular Systems Biology, ETH Zurich, Auguste-Piccard-Hof 1, 8093 Zürich, Switzerland.
Effy VayenaHealth Ethics and Policy Lab, Institute of Epidemiology, Biostatistics and Prevention, University of Zurich, Hirschengraben 84, 8001 Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore attitudes of Swiss older adults towards personal genomics (PG).

methodsUsing an anonymized voluntary paper-and-pencil survey, data were collected from 151 men and women aged 60-89 years attending the Seniorenuniversität Zurich, Switzerland (Seniors' University). Analyses were conducted using descriptive and inferential statistics.

resultsOne third of the respondents were aware of PG, and more than half indicated interest in undergoing PG testing. The primary motivation provided was respondents' interest in finding out about their own disease risk, followed by willingness to contribute to scientific research. Forty-four percent were not interested in undergoing testing because results might be worrisome, or due to concerns about the validity of the results. Only a minority of respondents mentioned privacy-related concerns. Further, 66% were interested in undergoing clinic-based PG motivated by the opportunity to contribute to scientific research (78%) and 75% of all study participants indicated strong preferences to donate genomic data to public research institutions.

conclusionThis study indicates a relatively positive overall attitude towards personal genomic testing among older Swiss adults, a group not typically represented in surveys about personal genomics. Genomic data of older adults can be highly relevant to late life health and maintenance of quality of life. In addition they can be an invaluable source for better understanding of longevity, health and disease. Understanding the attitudes of this population towards genomic analyses, although important, remains under-examined.

Indexed as

Attitudes of older adultsEthicsPersonal genomicsPersonalized medicinePrivacyResearch participation

Identifiers

PMID27047754
PMCPMC4796807

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.