Evidence map›Paper›PMID 27047646›Full record

ArticleInternational journal of hematology-oncology and stem cell research2016

T-cell/Natural killer-cell neoplasms presenting as leukemia- Case series from single tertiary care center.

Shano Naseem, Maninderbir Kaur, Manupdesh Singh Sachdeva, Jasmina Ahluwalia, Reena Das, Neelam Varma, Subhash Varma

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of hematology-oncology and stem cell research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shano NaseemAssistant Professor, Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh.
Maninderbir KaurSenior Resident, Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh.
Manupdesh Singh SachdevaAssistant Professor, Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh.
Jasmina AhluwaliaAssociate Professor, Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh.
Reena DasProfessor, Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh.
Neelam VarmaProfessor and Head, Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh.
Subhash VarmaProfessor and Head, Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMature T/ NK-cell neoplasms are a rare group of disorders and their presentation as leukemia is even rarer. Most of the previous studies have focused on mature B-cell lineage leukemias and there is a paucity of data on mature T/NK-cell lineage leukemias. We, therefore, planned this study to analyze their spectrum, frequency, morphology and immunophenotypic features. SUBJECTS AND

methodsAll cases of lymphomas presenting as leukemia over a period of two and a half years were evaluated. Detailed analysis of cases with T/NK-cell lineage was done for their clinical, hematological and immunophenotypic features.

resultsA total of 262 cases of mature lymphoid neoplasms presented as leukemia during the study period. Of whom, only 8 (3.1%) cases were of T /NK-cell lineage and the remaining (96.9%) were of B-cell lineage. Of 8 cases, 4 (50%) had T-prolymphocytic leukemia, 2 (25%) had chronic lymphoproliferative disorder- natural killer cell and 1 (12.5%) case of each T-large granular lymphocytic leukemia and hepatosplenic γ/δ T-NHL.

conclusionT/NK-cell leukemias are rare. Along with clinical and morphological features, pattern of immunophenotypic markers is vital for their diagnosis and subcategorization.

Indexed as

ImmunophenotypingMorphologyNK-lineage leukemiaT-lineage leukemia

Identifiers

PMID27047646
PMCPMC4818784
OpenAlexW2238008246

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.