ArticleFrontiers in plant science2016
High Quality Maize Centromere 10 Sequence Reveals Evidence of Frequent Recombination Events.
Article in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Article
- Article
- Individual plant genetics reveal the control of local adaptation in European maize landraces.BMC biology · 2025Article
- The structure, function, and evolution of plant centromeres.Genome research · 2024Review
- Centromere Plasticity With Evolutionary Conservation and Divergence Uncovered by Wheat 10+ Genomes.Molecular biology and evolution · 2023Article
- Article
- Characterization of centromeric DNA of Gossypium anomalum reveals sequence-independent enrichment dynamics of centromeric repeats.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2023Article
- The genetics and epigenetics of satellite centromeres.Genome research · 2022Article
- Diverse mechanisms of centromere specification.Current biology : CB · 2021Review
- High-throughput retrotransposon-based genetic diversity of maize germplasm assessment and analysis.Molecular biology reports · 2020Article
- Genome Evolution in Arabideae Was Marked by Frequent Centromere Repositioning.The Plant cell · 2020Article
- Back-spliced RNA from retrotransposon binds to centromere and regulates centromeric chromatin loops in maize.PLoS biology · 2020Article
- The Genomic Landscape of Centromeres in Cancers.Scientific reports · 2019Article
- Islands of retroelements are major components of Drosophila centromeres.PLoS biology · 2019Article
- Comparison ofThe Plant cell · 2018Article
- Epigenetic activation of meiotic recombination nearGenome research · 2018Article
- Stable centromere positioning in diverse sequence contexts of complex and satellite centromeres of maize and wild relatives.Genome biology · 2017Article
- Single-molecule sequencing resolves the detailed structure of complex satellite DNA loci inGenome research · 2017Article
- Meiotic Crossing Over in Maize Knob Heterochromatin.Genetics · 2017Article
- Article
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12 authors.
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Abstract
The ancestral centromeres of maize contain long stretches of the tandemly arranged CentC repeat. The abundance of tandem DNA repeats and centromeric retrotransposons (CR) has presented a significant challenge to completely assembling centromeres using traditional sequencing methods. Here, we report a nearly complete assembly of the 1.85 Mb maize centromere 10 from inbred B73 using PacBio technology and BACs from the reference genome project. The error rates estimated from overlapping BAC sequences are 7 × 10(-6) and 5 × 10(-5) for mismatches and indels, respectively. The number of gaps in the region covered by the reassembly was reduced from 140 in the reference genome to three. Three expressed genes are located between 92 and 477 kb from the inferred ancestral CentC cluster, which lies within the region of highest centromeric repeat density. The improved assembly increased the count of full-length CR from 5 to 55 and revealed a 22.7 kb segmental duplication that occurred approximately 121,000 years ago. Our analysis provides evidence of frequent recombination events in the form of partial retrotransposons, deletions within retrotransposons, chimeric retrotransposons, segmental duplications including higher order CentC repeats, a deleted CentC monomer, centromere-proximal inversions, and insertion of mitochondrial sequences. Double-strand DNA break (DSB) repair is the most plausible mechanism for these events and may be the major driver of centromere repeat evolution and diversity. In many cases examined here, DSB repair appears to be mediated by microhomology, suggesting that tandem repeats may have evolved to efficiently repair frequent DSBs in centromeres.
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