Evidence map›Paper›PMID 27047441›Full record

ReviewFrontiers in neurology2016

Role of Anticonvulsants in the Management of Posttraumatic Epilepsy.

Batool F Kirmani, Diana Mungall Robinson, Ekokobe Fonkem, Kevin Graf, Jason H Huang

Abstract readReview
In one paragraph

Review in Frontiers in neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Acute Treatment with the M-Channel (KNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Prevention of brain damage after traumatic brain injury by pharmacological enhancement of KCNQ (Kv7, "M-type") KJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Batool F KirmaniEpilepsy Center, Department of Neurology, Baylor Scott & White Health Neuroscience Institute, Texas A&M Health Science Center College of Medicine , Temple, TX , USA.
Diana Mungall RobinsonDepartment of Psychiatry, University of Virginia Medical Center , Charlottesville, VA , USA.
Ekokobe FonkemDivision of Neuro-oncology, Department of Neurosurgery, Baylor Scott & White Health Neuroscience Institute, Texas A&M Health Science Center College of Medicine , Temple, TX , USA.
Kevin GrafDivision of Neuro-oncology, Department of Neurosurgery, Baylor Scott & White Health Neuroscience Institute, Texas A&M Health Science Center College of Medicine , Temple, TX , USA.
Jason H HuangDepartment of Neurosurgery, Baylor Scott & White Health Neuroscience Institute, Texas A&M Health Science Center College of Medicine , Temple, TX , USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Posttraumatic seizures (PTS) have been recognized as a major complication of traumatic brain injury (TBI). The annual incidence of TBI in the United States is 1.7 million. The role of anticonvulsants in the treatment of posttraumatic epilepsy (PTE) remains uncertain. Based on current studies, however, anticonvulsants have been shown to reduce early PTS occurring within the first 7 days, but little to no benefits have been shown in late PTS occurring after 7 days. In this paper, we provide a mini review of the role of anticonvulsants and current advances in the management of PTE.

Indexed as

anticonvulsantsepilepsymanagementposttraumatic seizurestraumatic brain injury

Identifiers

PMID27047441
PMCPMC4801868

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.