ArticleFrontiers in physiology2016
Transcriptome Analysis of Differentially Expressed Genes Involved in Proanthocyanidin Accumulation in the Rhizomes of Fagopyrum dibotrys and an Irradiation-Induced Mutant.
Article in Frontiers in physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Complete mitochondrial genome assembly and comparative analysis of Fagopyrum dibotrys (Golden Buckwheat).BMC plant biology · 2025Article
- Effects ofFrontiers in veterinary science · 2025Article
- Genomics and resequencing ofFrontiers in plant science · 2024Article
- Succession of endophytic fungi and rhizosphere soil fungi and their correlation with secondary metabolites inFrontiers in microbiology · 2023Article
- Comparative transcriptomic and metabolomic analyses reveal differences in flavonoid biosynthesis between PCNA and PCA persimmon fruit.Frontiers in plant science · 2023Article
- The spatiotemporal regulations of epicatechin biosynthesis under normal flowering and the continuous inflorescence removal treatment in Fagopyrum dibotrys.BMC plant biology · 2022Article
- Transcriptome and HPLC Analysis Reveal the Regulatory Mechanisms of Aurantio-Obtusin in Space Environment-InducedInternational journal of environmental research and public health · 2022Article
- Integrated Transcriptomics and Widely Targeted Metabolomics Analyses Provide Insights Into Flavonoid Biosynthesis in the Rhizomes of Golden Buckwheat (Frontiers in plant science · 2022Article
- Towards a better understanding of Fagopyrum dibotrys: a systematic review.Chinese medicine · 2021Review
- Article
- Complete chloroplast genome sequence of Fagopyrum dibotrys: genome features, comparative analysis and phylogenetic relationships.Scientific reports · 2018Article
- Gene Profiling in Late Blight Resistance in Potato Genotype SD20.International journal of molecular sciences · 2018Article
- Neuraminidase Inhibitory Activity and Constituent Characterization of Fagopyrum dibotrys.Molecules (Basel, Switzerland) · 2017Article
- Transcriptome analysis of filling stage seeds among three buckwheat species with emphasis on rutin accumulation.PloS one · 2017Article
- Biorhizome: A Biosynthetic Platform for Colchicine Biomanufacturing.Frontiers in plant science · 2017Review
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2 authors.
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Abstract
The rhizome of Fagopyrum dibotrys is a traditional Chinese medicine that has recently gained attention due to substantial findings regarding its bioactive proanthocyanidin (PA) compounds. However, the molecular mechanism underlying PA accumulation in F. dibotrys remains elusive. We previously obtained an irradiation-induced mutant (RM_R) of F. dibotrys that had a higher PA content compared to that of the wild-type (CK_R). The present study aimed to elucidate the molecular mechanism underlying PA accumulation in F. dibotrys by comparing the rhizome transcriptomes of the irradiation-induced mutant and wild-type using RNA-seq analysis. A total of 53,540 unigenes were obtained, of which 29,901 (55.84%) were annotated based on BLAST searches against public databases, and 501 unique sequences were differentially expressed between the two samples, which consisted of 204 up-regulated and 297 down-regulated unigenes. Further analysis showed that the expression patterns of some unigenes encoding enzymes involved in PAs biosynthesis in F. dibotrys rhizomes differed between RM_R and CK_R. In addition, we identified transcription factor families and several cytochrome P450s that may be involved in PA regulation in F. dibotrys. Finally, 12 unigenes that encode PA biosynthetic enzymes were confirmed by qRT-PCR analysis. This study sheds light on the molecular mechanism underlying radiation-mediated flavonoid accumulation and regulation in F. dibotrys rhizomes. These results will also provide a platform for further functional genomic research on this particular species.
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