Evidence map›Paper›PMID 27047215›Full record

ArticleJournal of orthopaedics2015

Radiological and histopathological examination of apparent lytic lesions in allograft long bones-No cause for concern.

Mike Kent, Greg Brooker, Ryan Fisher, Geraldine Goh, Ranieri Falcao Aguiar, John Papadimitriou, Daniel Wong, Richard Carey-Smith, Anne Cowie

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of orthopaedics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mike KentPlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia.
Greg BrookerPlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia.
Ryan FisherPlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia.
Geraldine GohPlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia.
Ranieri Falcao AguiarDepartment of Radiology, Sir Charles Gairdner Hospital, Perth 6009, Western Australia Australia.
John PapadimitriouPlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia; PathWest, Sir Charles Gairdner Hospital, Perth 6009, Western Australia Australia.
Daniel WongPathWest, Sir Charles Gairdner Hospital, Perth 6009, Western Australia Australia.
Richard Carey-SmithPlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia.
Anne CowiePlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia.
Sir Charles Gairdner Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIdentify the nature of apparent lytic lesions within human allograft specimens from patients with no known malignancy, using radiological and histopathological analysis.

methods123 Post-retrieval radiographs from 23 donors were examined. Sixty-seven radiographs were noted to show apparent lytic lesions. The number, size, character and position of the apparent lesions were recorded.

resultsCT scanning of 9 specimens confirmed the lesions to be of air pockets causing artefact. Histopathological analysis showed no malignant or pathological process.

conclusionsApparent lesions were not pathological. PRACTICE IMPLICATIONS: Specimens with similar appearances, in donors with no malignancy, can be safely used in donation.

Indexed as

Bone and tissue bankingLong bone allograftsLytic lesionsQuality controlTumour reconstruction

Identifiers

PMID27047215
PMCPMC4796581
OpenAlexW2180237168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.