ArticleVeterinary world2015
Isolation and in vitro selection of actinomycetes strains as potential probiotics for aquaculture.
Article in Veterinary world, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Indigenous actinomycetes of the Himalaya: current knowledge and a bioinformatics perspective on plant growth-promoting and cold-tolerance traits.Archives of microbiology · 2026Review
- Phenotypic and safety exploration of indigenous bacterial strains for probiotic applications in aquaculture.BMC microbiology · 2025Article
- Integrated Omics-Based Discovery of Bioactive Halogenated Metabolites from the Deep-SeaMarine drugs · 2025Article
- Investigation of anti-microbial and cytotoxic potential of Streptomyces werraensis GRS9 derived from the sediments of river Ganga.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Article
- Advancing aquaculture probiotic discovery via an innovative protocol for isolation of indigenous, heat and salt tolerant, quorum quenching probiotic candidates.Frontiers in microbiology · 2025Article
- Influenza a virus subtype H9N2 infection induces respiratory microbiota dysbiosis in chickens via type-I interferon-mediated mechanisms.FEMS microbes · 2025Article
- Seasonal variations in composition and function of gut microbiota in grazing yaks: Implications for adaptation to dietary shift on the Qinghai-Tibet plateau.Ecology and evolution · 2024Article
- Review
- Polyenic Antibiotics and Other Antifungal Compounds Produced by HemolyticInternational journal of molecular sciences · 2022Review
- The Potential of Phylogenetically Diverse Culturable Actinobacteria fromTropical life sciences research · 2022Article
- Seasonal variation in structure and function of gut microbiota inEcology and evolution · 2022Article
- Characterization of Actinobacterial Strains as Potential Biocontrol Agents againstPlants (Basel, Switzerland) · 2022Article
- The Combined Use ofFrontiers in microbiology · 2022Article
- Marine Actinomycetes, New Sources of Biotechnological Products.Marine drugs · 2021Review
- Synergistic Antimicrobial Effect of a Seaweed-Probiotic Blend Against Acute Hepatopancreatic Necrosis Disease (AHPND)-Causing Vibrio parahaemolyticus.Probiotics and antimicrobial proteins · 2020Article
- Effect of Streptomyces probiotics on the gut microbiota of Litopenaeus vannamei challenged with Vibrio parahaemolyticus.MicrobiologyOpen · 2020Article
- Characterization ofInternational journal of microbiology · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThis study was designed to describe a series of in vitro tests that may aid the discovery of probiotic strains from actinomycetes. MATERIALS AND
methodsActinomycetes were isolated from marine sediments using four different isolation media, followed by antimicrobial activity and toxicity assessment by the agar diffusion method and the hemolysis of human blood cells, respectively. Extracellular enzymatic production was monitored by the hydrolysis of proteins, lipids and carbohydrates. Tolerance to different pH values and salt concentrations was also determined, followed by hydrophobicity analysis and genetic identification of the most promising strains.
resultsFive out of 31 isolated strains showed antimicrobial activity against three Vibrio species. Three non-hemolytic strains (N7, RL8 and V4) among these active isolates yielded positive results in hydrophobicity tests and exhibited good growth at salt concentrations ranging from 0% to 10%, except strain RL8, which required a salt concentration >0.6%. Although these strains did not grow at pH<3, they showed different enzymatic activities. Phylogenetic analysis revealed that strains N7 and V4 have more than 99% identity with several Streptomyces species, whereas the closest matches to strain RL8 are Streptomyces panacagri and Streptomyces flocculus, with 98% and 98.2% similarity, respectively.
conclusionThree actinomycetes strains showing probiotic-like properties were discovered using several in vitro tests that can be easily implemented in different institutions around the world.
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