Evidence map›Paper›PMID 27046940›Full record

ArticleMikrochimica acta2016

Optofluidic devices with integrated solid-state nanopores.

Shuo Liu, Aaron R Hawkins, Holger Schmidt

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mikrochimica acta, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Biosensors-on-Chip: An Up-to-Date Review.Molecules (Basel, Switzerland) · 2020
    Review
  5. Article
  6. Optofluidic bioanalysis: fundamentals and applications.Nanophotonics (Berlin, Germany) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shuo LiuSchool of Engineering, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA.
Aaron R HawkinsECEn Department, 459 Clyde Building, Brigham Young University, Provo, UT 84602, USA.
Holger SchmidtSchool of Engineering, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA.

Funding

Hybrid integrated molecular analysis (HIMAS) for point-of-care diagnosticsR33AI100229 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI SCHMIDT, HOLGER · 2014 to 2016
$1.7M
Single biomolecule sensors using integrated optical waveguides with liquid coresR01EB006097 · NIBIB · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI SCHMIDT, HOLGER · 2006 to 2009
$1.6M
Integrated Optical Particle Trap for Biomolecule Analysis and ManipulationR21EB008802 · NIBIB · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI SCHMIDT, HOLGER · 2009 to 2010
$399k
NIAID NIH HHS R33 AI100229NIBIB NIH HHS R01 EB006097NIBIB NIH HHS R21 EB008802
6 · The paper itself

Abstract

This review (with 90 refs.) covers the state of the art in optofluidic devices with integrated solid-state nanopores for use in detection and sensing. Following an introduction into principles of optofluidics and solid-state nanopore technology, we discuss features of solid-state nanopore based assays using optofluidics. This includes the incorporation of solid-state nanopores into optofluidic platforms based on liquid-core anti-resonant reflecting optical waveguides (ARROWs), methods for their fabrication, aspects of single particle detection and particle manipulation. We then describe the new functionalities provided by solid-state nanopores integrated into optofluidic chips, in particular acting as smart gates for correlated electro-optical detection and discrimination of nanoparticles. This enables the identification of viruses and λ-DNA, particle trajectory simulations, enhancing sensitivity by tuning the shape of nanopores. The review concludes with a summary and an outlook.

Indexed as

ARROW waveguidesBioassayElectro-opticsFluorescence analysisLiquid core waveguideParticle manipulationSingle biomolecule detectionSystem integration

Identifiers

PMID27046940
PMCPMC4817374

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.