ArticlePloS one2016
Male Lineages in Brazil: Intercontinental Admixture and Stratification of the European Background.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Genetic insights into the peoples who shaped the American continent.Genetics and molecular biology · 2026Article
- Tracing the Uncharted African Diaspora in Southern Brazil: The Genetic Legacies of Resistance in TwoGenes · 2025Article
- Mitochondrial ancestry from complete mitogenomes highlights a lack of characterization of indigenous haplogroups in Brazilian Amazon population.Communications biology · 2025Article
- Application of Targeted Y-Chromosomal Capture Enrichment to Increase the Resolution of Native American Haplogroup Q.Human mutation · 2024Article
- Human N-acetyltransferase 2 (Frontiers in pharmacology · 2023Article
- Article
- Uniparental markers reveal new insights on subcontinental ancestry and sex-biased admixture in Brazil.Molecular genetics and genomics : MGG · 2022Article
- The Ancestry of Eastern Paraguay: A Typical South American Profile with a Unique Pattern of Admixture.Genes · 2021Article
- Phylogeographic review of Y chromosome haplogroups in Europe.International journal of legal medicine · 2021Review
- Genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in Type 1 Diabetes from an admixed Brazilian population.Scientific reports · 2021Article
- New insights on intercontinental origins of paternal lineages in Northeast Brazil.BMC evolutionary biology · 2020Article
- Glycogen storage diseases: Twenty-seven new variants in a cohort of 125 patients.Molecular genetics & genomic medicine · 2019Article
- A single nucleotide polymorphism panel for individual identification and ancestry assignment in Caucasians and four East and Southeast Asian populations using a machine learning classifier.Forensic science, medicine, and pathology · 2019Article
- Article
- CBS mutations are good predictors for B6-responsiveness: A study based on the analysis of 35 Brazilian Classical Homocystinuria patients.Molecular genetics & genomic medicine · 2018Article
- Article
- mtDNA structure: the women who formed the Brazilian Northeast.BMC evolutionary biology · 2017Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The non-recombining nature of the Y chromosome and the well-established phylogeny of Y-specific Single Nucleotide Polymorphisms (Y-SNPs) make them useful for defining haplogroups with high geographical specificity; therefore, they are more apt than the Y-STRs to detect population stratification in admixed populations from diverse continental origins. Different Y-SNP typing strategies have been described to address issues of population history and movements within geographic territories of interest. In this study, we investigated a set of 41 Y-SNPs in 1217 unrelated males from the five Brazilian geopolitical regions, aiming to disclose the genetic structure of male lineages in the country. A population comparison based on pairwise FST genetic distances did not reveal statistically significant differences in haplogroup frequency distributions among populations from the different regions. The genetic differences observed among regions were, however, consistent with the colonization history of the country. The sample from the Northern region presented the highest Native American ancestry (8.4%), whereas the more pronounced African contribution could be observed in the Northeastern population (15.1%). The Central-Western and Southern samples showed the higher European contributions (95.7% and 93.6%, respectively). The Southeastern region presented significant European (86.1%) and African (12.0%) contributions. The subtyping of the most frequent European lineage in Brazil (R1b1a-M269) allowed differences in the genetic European background of the five Brazilian regions to be investigated for the first time.
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