Evidence map›Paper›PMID 27046163›Full record

ReviewWiley interdisciplinary reviews. RNA2016

The evolving world of small RNAs from RNA viruses.

Mei-Ling Li, Kuo-Feng Weng, Shin-Ru Shih, Gary Brewer

Open access · greenAbstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. RNA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
7.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Soybean Resistance to Soybean Mosaic Virus.Plants (Basel, Switzerland) · 2020
    Review
  10. RNA regulatory processes in RNA virus biology.Wiley interdisciplinary reviews. RNA · 2019
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. What Really Rigs Up RIG-I?Journal of innate immunity · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Mei-Ling LiDepartment of Biochemistry & Molecular Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.
Kuo-Feng WengResearch Center for Emerging Viral Infections, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Shin-Ru ShihResearch Center for Emerging Viral Infections, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Gary BrewerDepartment of Biochemistry & Molecular Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ, USA.
Chang Gung Memorial Hospital · TWChang Gung University · TWJohnson University · USRutgers, The State University of New Jersey · US

Funding

POST TRANSCRIPTIONAL REGULATION--ONCOGENE MESSENGER RNAR01CA052443 · NCI · WAKE FOREST UNIVERSITY · PI BREWER, GARY A. · 1990 to 2012
$4.3M
NCI NIH HHS R01 CA052443
6 · The paper itself

Abstract

RNA virus infection in plants and invertebrates can produce virus-derived small RNAs. These RNAs share features with host endogenous small interfering RNAs (siRNAs). They can potentially mediate RNA interference (RNAi) and related RNA silencing pathways, resulting in specific antiviral defense. Although most RNA silencing components such as Dicer, Ago2, and RISC are conserved among eukaryotic hosts, whether RNA virus infection in mammals can generate functional small RNAs that act in antiviral defense remains under discussion. Here, we review recent studies on the molecular and biochemical features of viral siRNAs and other virus-derived small RNAs from infected plants, arthropods, nematodes, and vertebrates and discuss the genetic pathways for their biogenesis and their roles in antiviral activity. WIREs RNA 2016, 7:575-588. doi: 10.1002/wrna.1351 For further resources related to this article, please visit the WIREs website.

Indexed as

Gene SilencingHost-Pathogen InteractionsAnimalsInvertebratesPlantsRNA, Small UntranslatedRNA, ViralRNA VirusesVertebratesRNA, Small UntranslatedRNA, Viral

Identifiers

PMID27046163
PMCPMC5722025
OpenAlexW2336458593

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.