Evidence map›Paper›PMID 27045924›Full record

ArticleThe American journal of gastroenterology2016

Decreasing Mortality Among Danish Alcoholic Cirrhosis Patients: A Nationwide Cohort Study.

Thomas Deleuran, Hendrik Vilstrup, Peter Jepsen

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In one paragraph

Article in The American journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Non-invasive tests for MetALD and alcohol-related liver disease.JHEP reports : innovation in hepatology · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Population screening for cirrhosis.Hepatology communications · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Contemporary Epidemiology of Chronic Liver Disease and Cirrhosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2020
    Review
  13. Observational
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Thomas DeleuranDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Hendrik VilstrupDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Peter JepsenDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Aarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesClinical management of certain cirrhosis complications has improved over the last two decades. In this study we aimed to examine whether mortality among Danish alcoholic cirrhosis patients has decreased during this period.

methodsIn this historical cohort study we used nationwide hospital data to identify Danish alcoholic cirrhosis patients diagnosed in 1996-1998, 1999-2001, 2002-2004, 2005-2007, 2008-2010, and 2011-2013. We used Cox regression to examine time trends in mortality after cirrhosis diagnosis, adjusting for confounding by age, gender, and prevalence of variceal bleeding, ascites, hepatorenal syndrome, alcoholic hepatitis, infection, hepatocellular carcinoma, comorbidity, and in-patient status at the time of cirrhosis diagnosis.

resultsWe included 22,734 patients (69% men). The adjusted mortality hazard ratio (HR) for patients diagnosed in each period compared with those diagnosed in 1996-1998 was 0.99 (95% confidence interval (CI): 0.92-1.06) in 1999-2001, 1.00 (95% CI: 0.94-1.08) in 2002-2004, 0.97 (95% CI: 0.90-1.04) in 2005-2007, 0.94 (95% CI: 0.88-1.01) in 2008-2010, and finally 0.84 (95% CI: 0.79-0.90) in 2011-2013.

conclusionsIn recent years, mortality among Danish alcoholic cirrhosis patients has decreased.

Indexed as

AdultAgedAge FactorsComorbidityDenmarkFemaleHumansLiver Cirrhosis, AlcoholicMaleMiddle AgedMortalityPrevalencePrognosisSex Factors

Identifiers

PMID27045924
OpenAlexW2313462754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.