Evidence map›Paper›PMID 27045295›Full record

ArticlePloS one2016

Learning Effective Connectivity Network Structure from fMRI Data Based on Artificial Immune Algorithm.

Junzhong Ji, Jinduo Liu, Peipeng Liang, Aidong Zhang

Abstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Junzhong JiBeijing Municipal Key Laboratory of Multimedia and Intelligent Software, College of Computer Science and Technology, Beijing University of Technology, Beijing, China.
Jinduo LiuBeijing Municipal Key Laboratory of Multimedia and Intelligent Software, College of Computer Science and Technology, Beijing University of Technology, Beijing, China.
Peipeng LiangBeijing Key Lab of MRI and Brain Informatics, Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Aidong ZhangDepartment of Computer Science and Engineering, University at Buffalo, The State University of New York, Buffalo, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many approaches have been designed to extract brain effective connectivity from functional magnetic resonance imaging (fMRI) data. However, few of them can effectively identify the connectivity network structure due to different defects. In this paper, a new algorithm is developed to infer the effective connectivity between different brain regions by combining artificial immune algorithm (AIA) with the Bayes net method, named as AIAEC. In the proposed algorithm, a brain effective connectivity network is mapped onto an antibody, and four immune operators are employed to perform the optimization process of antibodies, including clonal selection operator, crossover operator, mutation operator and suppression operator, and finally gets an antibody with the highest K2 score as the solution. AIAEC is then tested on Smith's simulated datasets, and the effect of the different factors on AIAEC is evaluated, including the node number, session length, as well as the other potential confounding factors of the blood oxygen level dependent (BOLD) signal. It was revealed that, as contrast to other existing methods, AIAEC got the best performance on the majority of the datasets. It was also found that AIAEC could attain a relative better solution under the influence of many factors, although AIAEC was differently affected by the aforementioned factors. AIAEC is thus demonstrated to be an effective method for detecting the brain effective connectivity.

Indexed as

AlgorithmsBrainMagnetic Resonance ImagingModels, ImmunologicalModels, NeurologicalConnectomeHumansNerve NetRadiography

Identifiers

PMID27045295
PMCPMC4821460

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.