ArticlePloS one2016
Genetic Diversity and Genome Wide Association Study of β-Glucan Content in Tetraploid Wheat Grains.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 52 citations in OpenAlex.
- Genome-wide association analysis of fiber-related traits and identification of diagnostic SNP markers differentiating spelt wheat (Frontiers in plant science · 2026Article
- Genome-wide association study and KASP marker development for flour color in winter wheat.Scientific reports · 2025Article
- The Barley Glycosyltransferase GenePlants (Basel, Switzerland) · 2025Article
- Effects of Irrigation Water Amount and Humic Acid on β-Glucan Synthesis in Post-Anthesis Grains of Naked Oats.Life (Basel, Switzerland) · 2025Article
- Genome-wide association analysis and KASP markers development for protein quality traits in winter wheat.BMC plant biology · 2025Article
- Enhancing wheat β-glucan content through precision crossbreeding: development and evaluation of biofortified lines with improved nutritional and agronomic traits.Frontiers in genetics · 2025Article
- Is theFood chemistry. Molecular sciences · 2024Article
- Genome-wide association study and KASP marker development for starch quality traits in wheat.The plant genome · 2024Article
- Article
- Genetic Approaches to Increase Arabinoxylan and β-Glucan Content in Wheat.Plants (Basel, Switzerland) · 2023Review
- Influence of Hulling, Cleaning and Brushing/Polishing of (Pseudo)Cereal Grains on Compositional Characteristics.Foods (Basel, Switzerland) · 2023Article
- Unraveling the Potential of β-D-Glucans inLife (Basel, Switzerland) · 2023Review
- β-Glucan as a Techno-Functional Ingredient in Dairy and Milk-Based Products-A Review.Molecules (Basel, Switzerland) · 2022Review
- A consensus map for quality traits in durum wheat based on genome-wide association studies and detection of ortho-meta QTL across cereal species.Frontiers in genetics · 2022Article
- Comprehensive evaluation of mapping complex traits in wheat using genome-wide association studies.Molecular breeding : new strategies in plant improvement · 2022Review
- From Genetic Maps to QTL Cloning: An Overview for Durum Wheat.Plants (Basel, Switzerland) · 2021Review
- Proteome and Nutritional Shifts Observed in Hordein Double-Mutant Barley Lines.Frontiers in plant science · 2021Article
- Genome-Wide Association Mapping of Mixed Linkage (1,3;1,4)-β-Glucan and Starch Contents in Rice Whole Grain.Frontiers in plant science · 2021Article
- The Triple Jags of Dietary Fibers in Cereals: How Biotechnology IsFrontiers in plant science · 2021Review
- Wheat Breeding through Genetic and Physical Mapping.International journal of molecular sciences · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-starch polysaccharides (NSPs) have many health benefits, including immunomodulatory activity, lowering serum cholesterol, a faecal bulking effect, enhanced absorption of certain minerals, prebiotic effects and the amelioration of type II diabetes. The principal components of the NSP in cereal grains are (1,3;1,4)-β-glucans and arabinoxylans. Although (1,3;1,4)-β-glucan (hereafter called β-glucan) is not the most representative component of wheat cell walls, it is one of the most important types of soluble fibre in terms of its proven beneficial effects on human health. In the present work we explored the genetic variability of β-glucan content in grains from a tetraploid wheat collection that had been genotyped with a 90k-iSelect array, and combined this data to carry out an association analysis. The β-glucan content, expressed as a percentage w/w of grain dry weight, ranged from 0.18% to 0.89% across the collection. Our analysis identified seven genomic regions associated with β-glucan, located on chromosomes 1A, 2A (two), 2B, 5B and 7A (two), confirming the quantitative nature of this trait. Analysis of marker trait associations (MTAs) in syntenic regions of several grass species revealed putative candidate genes that might influence β-glucan levels in the endosperm, possibly via their participation in carbon partitioning. These include the glycosyl hydrolases endo-β-(1,4)-glucanase (cellulase), β-amylase, (1,4)-β-xylan endohydrolase, xylanase inhibitor protein I, isoamylase and the glycosyl transferase starch synthase II.
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