Evidence map›Paper›PMID 27044853›Full record

ArticlePhysiological reports2016

Maximal exercise does not increase ventilation heterogeneity in healthy trained adults.

Jeremy P Wrobel, Matthew J Ellis, Kirk Kee, Christopher R Stuart-Andrews, Bruce R Thompson

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jeremy P WrobelDepartment of Medicine, Monash University, Melbourne, Australia Allergy, Immunology & Respiratory Medicine, The Alfred, Melbourne, Australia Department of Respiratory Medicine, Fiona Stanley Hospital, Perth, Australia jeremy.wrobel@health.wa.gov.au.
Matthew J EllisAllergy, Immunology & Respiratory Medicine, The Alfred, Melbourne, Australia.
Kirk KeeDepartment of Medicine, Monash University, Melbourne, Australia Allergy, Immunology & Respiratory Medicine, The Alfred, Melbourne, Australia.
Christopher R Stuart-AndrewsAllergy, Immunology & Respiratory Medicine, The Alfred, Melbourne, Australia.
Bruce R ThompsonDepartment of Medicine, Monash University, Melbourne, Australia Allergy, Immunology & Respiratory Medicine, The Alfred, Melbourne, Australia.
Alfred Health · AUThe Alfred Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of exercise on ventilation heterogeneity has not been investigated. We hypothesized that a maximal exercise bout would increase ventilation heterogeneity. We also hypothesized that increased ventilation heterogeneity would be associated with exercise-induced arterial hypoxemia (EIAH). Healthy trained adult males were prospectively assessed for ventilation heterogeneity using lung clearance index (LCI), Scond, and Sacinat baseline, postexercise and at recovery, using the multiple breath nitrogen washout technique. The maximal exercise bout consisted of a maximal, incremental cardiopulmonary exercise test at 25 watt increments. Eighteen subjects were recruited with mean ± SDage of 35 ± 9 years. There were no significant changes inLCI, Scond, or Sacinfollowing exercise or at recovery. While there was an overall reduction in SpO2with exercise (99.3 ± 1 to 93.7 ± 3%,P < 0.0001), the reduction in SpO2was not associated with changes inLCI, Scondor Sacin Ventilation heterogeneity is not increased following a maximal exercise bout in healthy trained adults. Furthermore,EIAHis not associated with changes in ventilation heterogeneity in healthy trained adults.

Indexed as

ExercisePulmonary VentilationAdultBicyclingExercise TestHealthy VolunteersHumansHypoxiaLungMaleMiddle AgedProspective StudiesRecovery of FunctionTime FactorsCardiopulmonary exercise testhypoxemialung clearance indexmultiple breath nitrogen washoutventilation inhomogeneity

Identifiers

PMID27044853
PMCPMC4831321
OpenAlexW2340000565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.