Evidence map›Paper›PMID 27044795›Full record

ArticlePeritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

Rate of Decline of Residual Kidney Function Before and After the Start of Peritoneal Dialysis.

Lian He, Xihui Liu, Zi Li, Zita Abreu, Tushar Malavade, Charmaine E Lok, Joanne M Bargman

Abstract read
In one paragraph

Article in Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Transfers to Hemodialysis Among US Patients Initiating Renal Replacement Therapy With Peritoneal Dialysis.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2019
    Article
  10. Observational
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  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Lian HeDepartment of Nephrology, Peking University 3 Hospital, Beijing, P.R. China University Health Network, Toronto General Hospital and the University of Toronto, Toronto, ON, Canada.
Xihui LiuDivision of Nephrology, Linyi People's Hospital, Linyi, Shandong, P.R. China University Health Network, Toronto General Hospital and the University of Toronto, Toronto, ON, Canada.
Zi LiDepartment of Nephrology, West China Hospital, Chengdu, Sichuan, P.R. China University Health Network, Toronto General Hospital and the University of Toronto, Toronto, ON, Canada.
Zita AbreuUniversity Health Network, Toronto General Hospital and the University of Toronto, Toronto, ON, Canada.
Tushar MalavadeUniversity Health Network, Toronto General Hospital and the University of Toronto, Toronto, ON, Canada.
Charmaine E LokUniversity Health Network, Toronto General Hospital and the University of Toronto, Toronto, ON, Canada.
Joanne M BargmanUniversity Health Network, Toronto General Hospital and the University of Toronto, Toronto, ON, Canada Joanne.Bargman@uhn.ca.
Toronto General Hospital · CAUniversity Health Network · CAUniversity of Toronto · CASichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelled♦

backgroundThere is a paucity of information on whether peritoneal dialysis (PD) slows the decline of residual kidney function (RKF) compared to the natural slope of RKF decline prior to dialysis start. Our aim was to analyze the RKF decline before and after initiating PD, and to determine the principal factors affecting this decline during the PD period. ♦

methodsWe determined individual glomerular filtration rates (GFR) for approximately 12 months before and after PD in 77 new PD patients in a large academic medical center (2008 - 2012). The GFR was estimated by the Modification of Diet in Renal Disease (MDRD) equation in the predialysis period and by averaging 24-hour urine creatinine and urea clearances in the PD period. The rate of RKF decline was calculated using unadjusted linear regression analysis. Wilcoxon signed rank test was used to compare RKF decline before and after PD initiation. Multivariate linear regression was used to identify independent risk factors for RKF decline in the PD phase. ♦

resultsA significantly slower mean rate of RKF decline was observed in the PD period compared with the predialysis period (-0.21 ± 0.30 vs -0.59 ± 0.55 mL/min/1.73 m(2)/month, p < 0.01). Higher baseline RKF, higher serum phosphate, and older age were independently associated with faster decline of RKF (all p < 0.01). ♦

conclusionsIn patients with advanced chronic kidney disease, initiating PD was associated with a slower rate of RKF decline compared to the rate in the predialysis period.

Indexed as

Peritoneal DialysisAdultAgedDisease ProgressionFemaleGlomerular Filtration RateHumansKidney Failure, ChronicKidney Function TestsMaleMiddle AgedRetrospective StudiesTime FactorsPeritoneal dialysisrenal function declinerenal protection

Identifiers

PMID27044795
PMCPMC4881797
OpenAlexW2336180508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.