Observational studyBMC family practice2016
Combined effects of sleep quality and depression on quality of life in patients with type 2 diabetes.
Observational study in BMC family practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Understanding the relationship between sleep and quality of life in type 2 diabetes: A systematic review of the literature.Journal of health psychology · 2023Pooled it
- Prevalence of Insomnia (Symptoms) in T2D and Association With Metabolic Parameters and Glycemic Control: Meta-Analysis.The Journal of clinical endocrinology and metabolism · 2020Pooled it
- Chinese Taoist Cognitive Therapy for Symptoms of Depression and Anxiety in Adults in China: A Systematic Review and Meta-Analysis.Frontiers in psychology · 2020Pooled it
- To assess the impact of individualized strategy and continuous glucose monitoring on glycemic control and mental health in pregnant women with diabetes.Frontiers in endocrinology · 2025Trial
- The effects of melissa officinalis on depression and anxiety in type 2 diabetes patients with depression: a randomized double-blinded placebo-controlled clinical trial.BMC complementary medicine and therapies · 2023Trial
- Association of weekend catch-up sleep ratio with depressive risk: insights from NHANES 2021-2023.BMC psychiatry · 2025Article
- Concept analysis of diabetes-related quality of life.Health and quality of life outcomes · 2025Review
- Health-Related Quality of Life and Psychosocial Outcomes in Patients With Type 2 Diabetes Mellitus: A Bibliometric Analysis.Journal of diabetes research · 2025Review
- Relationship between sleep quality and depression in people with type 2 diabetes.Journal of diabetes and metabolic disorders · 2024Article
- [Cognition and depression in older people with diabetes].Der Nervenarzt · 2024Review
- The multimorbidity association of metabolic syndrome and depression on type 2 diabetes: a general population cohort study in Southwest China.Frontiers in endocrinology · 2024Article
- Stress and human health in diabetes: A report from the 19Journal of clinical and translational science · 2023Article
- Sleep Quality among Patients with Type 2 Diabetes: A Cross-Sectional Study in the East Coast Region of Peninsular Malaysia.International journal of environmental research and public health · 2022Article
- Globally altered sleep patterns and physical activity levels by confinement in 5056 individuals: ECLB COVID-19 international online survey.Biology of sport · 2021Article
- The influence of hypoglycemia on the specific quality of life in type 2 diabetes mellitus: a comparative cross-sectional study of diabetics with and without hypoglycemia in Xi'an, China.Health and quality of life outcomes · 2021Article
- Relationship Between Social Capital and Depressive Symptoms Among Type 2 Diabetes Mellitus Patients in Northwest China: A Mediating Role of Sleep Quality.Frontiers in psychiatry · 2021Article
- A comparison of diabetes self-care behavior in people with type 2 diabetes with and without insomnia symptoms.Acta diabetologica · 2020Article
- Sleep complaints in early pregnancy. A cross-sectional study among women attending prenatal care in general practice.BMC pregnancy and childbirth · 2020Article
- Sleep Quality and Associated Factors Among Diabetes Mellitus Patients in a Follow-Up Clinic at the University of Gondar Comprehensive Specialized Hospital in Gondar, Northwest Ethiopia: A Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Negative impact of COVID-19 pandemic on sleep quantitative parameters, quality, and circadian alignment: Implications for health and psychological well-being.EXCLI journal · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPoor sleep quality and depression negatively impact the health-related quality of life of patients with type 2 diabetes, but the combined effect of the two factors is unknown. This study aimed to assess the interactive effects of poor sleep quality and depression on the quality of life in patients with type 2 diabetes.
methodsPatients with type 2 diabetes (n = 944) completed the Diabetes Specificity Quality of Life scale (DSQL) and questionnaires on sleep quality and depression. The products of poor sleep quality and depression were added to the logistic regression model to evaluate their multiplicative interactions, which were expressed as the relative excess risk of interaction (RERI), the attributable proportion (AP) of interaction, and the synergy index (S).
resultsPoor sleep quality and depressive symptoms both increased DSQL scores. The co-presence of poor sleep quality and depressive symptoms significantly reduced DSQL scores by a factor of 3.96 on biological interaction measures. The relative excess risk of interaction was 1.08. The combined effect of poor sleep quality and depressive symptoms was observed only in women.
conclusionsPatients with both depressive symptoms and poor sleep quality are at an increased risk of reduction in diabetes-related quality of life, and this risk is particularly high for women due to the interaction effect. Clinicians should screen for and treat sleep difficulties and depressive symptoms in patients with type 2 diabetes.
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