ArticlePediatric radiology2016
Imaging of primary pediatric lymphoma of bone.
Article in Pediatric radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Spectrum of imaging findings of primary bone lymphoma in pediatric patients.Pediatric radiology · 2024Review
- Bone marrow edema in children: chronic nonbacterial osteomyelitis and its mimickers.Therapeutic advances in musculoskeletal disease · 2024Review
- MR features of primary bone lymphoma in children.Pediatric radiology · 2023Article
- Primary lymphoma of the tibia in children: Two case reports.Medicine · 2020Article
- Imaging mimics of chronic recurrent multifocal osteomyelitis: avoiding pitfalls in a diagnosis of exclusion.Pediatric radiology · 2020Review
- Challenges of assessing response to therapy in non-Hodgkin's lymphoma of the bone.BMJ case reports · 2018Article
- Non-odontogenic tumors of the facial bones in children and adolescents: role of multiparametric imaging.Neuroradiology · 2017Review
- Primary pediatric Burkitt's lymphoma of both femurs-case report.Hematology, transfusion and cell therapyArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary pediatric bone lymphoma is a rare form of non-Hodgkin lymphoma. Unlike nodal forms of lymphoma, imaging abnormalities in lymphoma of bone do not resolve rapidly in conjunction with treatment and radiologic findings can remain abnormal for years, making it difficult to evaluate treatment response.
objectiveTo evaluate the utility of imaging in assessment of patients with primary pediatric bone lymphoma. MATERIALS AND
methodsAt our institution between 2004 and 2013, six cases of pathology-proven primary pediatric bone lymphoma were diagnosed. Retrospective chart review was performed to assess imaging utilization. Our data were qualitatively compared with existing literature to construct an algorithm for imaging patients with primary lymphoma of bone.
resultsImaging evaluation of patients with primary pediatric bone lymphoma was highly variable at our institution. Conventional imaging was routinely used to evaluate response to treatment, despite lack of appreciable osseous change. Imaging in the absence of symptoms did not alter clinical management. Only positron emission tomography CT (PET/CT) proved capable of demonstrating imaging changes from the pretreatment to the post-treatment scans that were consistent with the clinical response to treatment.
conclusionSurveillance imaging is likely unnecessary in patients with a known diagnosis of pediatric lymphoma of bone. Pretreatment and post-treatment PET/CT is likely sufficient to assess response. There is little data to support the use of interim and surveillance PET/CT.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.