ArticleHuman genetics2016
Refining the Y chromosome phylogeny with southern African sequences.
Article in Human genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 94 citations in OpenAlex.
- Recovering the precolonial population structure of Khoe-San descendant populations.Science advances · 2026Article
- A high-resolution Y-chromosomal panel for forensic paternal lineage tracing and anthropological insight: unraveling the genetic structure of the Dongxiang ethnic minority.International journal of legal medicine · 2026Article
- Deciphering the genetic diversity in the Arabian Peninsula and Africa: insights from Y-STR data.Forensic science, medicine, and pathology · 2026Article
- Recovering the pre-colonial population structure of Khoe-San descendant populations.bioRxiv : the preprint server for biology · 2025Article
- Introducing the Y-chromosomal Ancestral-like Reference Sequence-Improving the Capture of Human Evolutionary Information.Molecular biology and evolution · 2025Article
- Article
- Resolving the source of branch length variation in the Y chromosome phylogeny.Genome biology · 2025Article
- BaTwa populations from Zambia retain ancestry of past hunter-gatherer groups.Nature communications · 2024Article
- Inferences about the population history ofEcology and evolution · 2024Article
- Refining the evolutionary tree of the horse Y chromosome.Scientific reports · 2023Article
- The recombination landscape of the Khoe-San likely represents the upper limits of recombination divergence in humans.Genome biology · 2022Article
- GWAS in the southern African context.PloS one · 2022Article
- Bantu-speaker migration and admixture in southern Africa.Human molecular genetics · 2021Review
- Searching for the roots of the first free African American community.Scientific reports · 2020Article
- Y-Chromosome Variation in Southern African Khoe-San Populations Based on Whole-Genome Sequences.Genome biology and evolution · 2020Article
- Article
- A Rare Deep-Rooting D0 African Y-Chromosomal Haplogroup and Its Implications for the Expansion of Modern Humans Out of Africa.Genetics · 2019Article
- Contrasting Paternal and Maternal Genetic Histories of Thai and Lao Populations.Molecular biology and evolution · 2019Article
- The evolutionary history of grey wolf Y chromosomes.Molecular ecology · 2019Article
- African evolutionary history inferred from whole genome sequence data of 44 indigenous African populations.Genome biology · 2019Article
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recent availability of large-scale sequence data for the human Y chromosome has revolutionized analyses of and insights gained from this non-recombining, paternally inherited chromosome. However, the studies to date focus on Eurasian variation, and hence the diversity of early-diverging branches found in Africa has not been adequately documented. Here, we analyze over 900 kb of Y chromosome sequence obtained from 547 individuals from southern African Khoisan- and Bantu-speaking populations, identifying 232 new sequences from basal haplogroups A and B. We identify new clades in the phylogeny, an older age for the root, and substantially older ages for some individual haplogroups. Furthermore, while haplogroup B2a is traditionally associated with the spread of Bantu speakers, we find that it probably also existed in Khoisan groups before the arrival of Bantu speakers. Finally, there is pronounced variation in branch length between major haplogroups; in particular, haplogroups associated with Bantu speakers have significantly longer branches. Technical artifacts cannot explain this branch length variation, which instead likely reflects aspects of the demographic history of Bantu speakers, such as recent population expansion and an older average paternal age. The influence of demographic factors on branch length variation has broader implications both for the human Y phylogeny and for similar analyses of other species.
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