ArticleAnalytical chemistry2016
State-of-the-Art Metabolic Toxicity Screening and Pathway Evaluation.
Article in Analytical chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 29 citations in OpenAlex.
- Metabolites of Tobacco- and E-Cigarette-Related Nitrosamines Can Drive CuChemical research in toxicology · 2020Article
- New Frontiers for Biofabrication and Bioreactor Design in Microphysiological System Development.Trends in biotechnology · 2019Review
- Recent advances in microfluidics for drug screening.Biomicrofluidics · 2019Review
- Pathways of Metabolite-Related Damage to a Synthetic p53 Gene Exon 7 Oligonucleotide Using Magnetic Enzyme Bioreactor Beads and LC-MS/MS Sequencing.Biochemistry · 2018Article
- Microfluidic Devices for Drug Assays.High-throughput · 2018Review
- Developing Microfluidic Sensing Devices Using 3D Printing.ACS sensors · 2018Article
- Evaluating Metabolite-Related DNA Oxidation and Adduct Damage from Aryl Amines Using a Microfluidic ECL Array.Analytical chemistry · 2017Article
- Modern Approaches to Chemical Toxicity Screening.Current opinion in electrochemistry · 2017Article
- Automated 3-D Printed Arrays to Evaluate Genotoxic Chemistry: E-Cigarettes and Water Samples.ACS sensors · 2017Article
- Screening Genotoxicity Chemistry with Microfluidic Electrochemiluminescent Arrays.Sensors (Basel, Switzerland) · 2017Review
- Bystander signaling via oxidative metabolism.OncoTargets and therapy · 2017Review
- Microfluidic array for simultaneous detection of DNA oxidation and DNA-adduct damage.The Analyst · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Routine in vitro bioassays and animal toxicity studies of drug and environmental chemical candidates fail to reveal toxicity in ∼30% of cases. This Feature article addresses research on new approaches to in vitro toxicity testing as well as our own efforts to produce high-throughput genotoxicity arrays and LC-MS/MS approaches to reveal possible chemical pathways of toxicity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.