Evidence map›Paper›PMID 27042902›Full record

ReviewContinuum (Minneapolis, Minn.)2016

Alzheimer Disease.

Liana G Apostolova

Abstract readReview
In one paragraph

Review in Continuum (Minneapolis, Minn.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
  8. Usefulness ofInternational journal of molecular sciences · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Nanoparticles as an Encouraging Therapeutic Approach to Alzheimer's Disease.International journal of molecular sciences · 2025
    Review
  15. Review
  16. Article
  17. Article
  18. Excess Wnt in neurological disease.The Biochemical journal · 2025
    Review
  19. Article
  20. Review

57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Liana G Apostolova

Funding

Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 1991 to 2020
$37.3M
Imaging and genetic biomarkers for Alzheimer's diseaseR01AG040770 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI APOSTOLOVA, LIANA G · 2012 to 2016
$1.4M
Imaging epigenetics of Alzheimer's DiseaseK02AG048240 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI APOSTOLOVA, LIANA G · 2014 to 2016
$434k
NIA NIH HHS K02 AG048240NIA NIH HHS NIA K02AG048240NIA NIH HHS NIA P30 AG010133NIA NIH HHS NIA R01 AG040770NIA NIH HHS P30 AG010133NIA NIH HHS R01 AG040770
6 · The paper itself

Abstract

purpose of reviewThis article discusses the recent advances in the diagnosis and treatment of Alzheimer disease (AD). RECENT

findingsIn recent years, significant advances have been made in the fields of genetics, neuroimaging, clinical diagnosis, and staging of AD. One of the most important recent advances in AD is our ability to visualize amyloid pathology in the living human brain. The newly revised criteria for diagnosis of AD dementia embrace the use for biomarkers as supportive evidence for the underlying pathology. Guidelines for the responsible use of amyloid positron emission tomography (PET) have been developed, and the clinical and economic implications of amyloid PET imaging are actively being explored. SUMMARY: Our improved understanding of the clinical onset, progression, neuroimaging, pathologic features, genetics, and other risk factors for AD impacts the approaches to clinical diagnosis and future therapeutic interventions.

Indexed as

Alzheimer DiseaseCognition DisordersDisease ProgressionHumansNeuropsychological TestsPsychiatric Status Rating Scales

Identifiers

PMID27042902
PMCPMC5390933

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.