Evidence map›Paper›PMID 27042605›Full record

ArticleNorth American journal of medical sciences2016

Differences in Severity and Outcomes Between Hypertriglyceridemia and Alcohol-Induced Pancreatitis.

Hemant Goyal, Betsy Smith, Chelsey Bayer, Carla Rutherford, Danielle Shelnut

Abstract read
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In one paragraph

Article in North American journal of medical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Pooled it
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Comparative study of the outcome between alcohol and gallstone pancreatitis in a high-volume tertiary care center.JGH open : an open access journal of gastroenterology and hepatology · 2019
    Article
  14. Review
  15. Food-Induced Acute Pancreatitis.Digestive diseases and sciences · 2017
    Review
  16. Review
  17. Severity and outcomes of acute alcoholic pancreatitis in cannabis users.Translational gastroenterology and hepatology · 2017
    Article
  18. Risk factors associated with intolerance to enteral nutrition in moderately severe acute pancreatitis: A retrospective study of 568 patients.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hemant GoyalDepartment of Internal Medicine, The Medical Center, Navicent Health and Mercer University School of Medicine, Macon, Georgia, USA.
Betsy SmithDepartment of Internal Medicine, The Medical Center, Navicent Health and Mercer University School of Medicine, Macon, Georgia, USA.
Chelsey BayerDepartment of Internal Medicine, The Medical Center, Navicent Health and Mercer University School of Medicine, Macon, Georgia, USA.
Carla RutherfordDepartment of Internal Medicine, The Medical Center, Navicent Health and Mercer University School of Medicine, Macon, Georgia, USA.
Danielle ShelnutDepartment of Internal Medicine, The Medical Center, Navicent Health and Mercer University School of Medicine, Macon, Georgia, USA.
Mercer University · USNavicent Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlcohol and hypertriglyceridemia (HTG) are among the most common causes of acute pancreatitis (AP) after gallstones. However, differences in severity at the time of presentation and outcomes have not been well-studied.

objectiveThe aim of this study is to assess the differences between severity at presentation and outcomes of AP of hypertriglyceridemic and alcoholic origins. MATERIALS AND

methodsA retrospective review of 177 patients who were discharged with diagnosis of AP was performed. Severity at presentation was identified by the presence of systemic inflammatory response syndrome, bedside index for severity in AP (BISAP) score, and Balthazar index. Outcomes were measured by the length of stay, intensive care unit care, surgical intervention, and mortality.

resultsWe found 147 patients with alcoholic pancreatitis and 30 patients with hypertriglyceridemic pancreatitis. A larger percentage of hypertriglyceridemic pancreatitis patients (23.33%) had a BISAP score of ≥2 compared to the alcoholic group (12.24%). Only 32.65% of the patients with alcoholic pancreatitis but 60% of the patients with hypertriglyceridemic pancreatitis had the presence of systemic inflammatory response syndrome (SIRS) at admission (P = 0.0067). There were 73.34% hypertriglyceridemic pancreatits patients and only 40.28% alcoholic pancreatitis patients with Balthazar index C or greater, suggesting a higher disease burden at admission for hypertriglyceridemic pancreatitis patients (P = 0.0047). There was a statistically significant difference in the relative number of hypertriglyceridemic and alcoholic pancreatitis patients receiving intensive care (P = 0.00030) and in receiving surgical interventions related to pancreatitis (P = 0.016).

conclusionOur study found that patients with hypertriglyceridemic pancreatitis have a greater severity of disease and they experience less favorable outcomes than patients with alcoholic pancreatitis.

Indexed as

Alcoholic pancreatitishypertriglyceridemic pancreatitisoutcomeseverity

Identifiers

PMID27042605
PMCPMC4791903
OpenAlexW2278872585

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LicenceCC BY-NC-SA
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.