ArticleJournal of clinical and diagnostic research : JCDR2016
A Hospital Based Study to Establish the Correlation between Recurrent Wheeze and Vitamin D Deficiency Among Children of Age Group Less than 3 Years in Indian Scenario.
Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- High burden of hypovitaminosis D among the children and adolescents in South Asia: a systematic review and meta-analysis.Journal of health, population, and nutrition · 2022Pooled it
- Article
- Vitamin D Level and Immune Modulation in Children with Recurrent Wheezing.Children (Basel, Switzerland) · 2024Article
- Association of 25-hydroxy vitamin D with asthma and its severity in children: a case-control study.Clinical and molecular allergy : CMA · 2020Article
- Prevalence of vitamin D deficiency and its relationship with factors associated with recurrent wheezing.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2019Article
- Vitamin D Status and Recurrent Wheezing in Infancy: Is There a Link?Indian journal of pediatrics · 2016Article
- Vitamin D Status in Infants with Two Different Wheezing Phenotypes.Indian journal of pediatrics · 2016Article
- The relation between serum vitamin D levels, viral infections and severity of attacks in children with recurrent wheezing.Allergologia et immunopathologiaArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEarly childhood wheezing is a heterogeneous condition, which has several phenotypic expressions and a complex relationship with the development of asthma later in life. New studies indicate the prevalence of recurrent wheeze to be associated with Vitamin D deficiency. This has not been explored in Indian settings widely, mandating this exploration.
aimTo determine the severity of Vitamin D deficiency and its association with recurrent wheeze in children less than 3 years of age. MATERIALS AND
methodsConsecutive type of non-probability sampling was followed for selection of study subjects with a total sample size to be 122 children in the Hospital setting. A pre- formed, pre- tested, structured interview schedule was used to obtain information. Estimation of 25 (OH) Vitamin D was done using ELISA method. Kit used for estimation was DLD Diagnostika GMBH 25(OH) Vitamin D ELISA from Germany. Standard statistical tools were used including Logistic regression analysis, and ROC curve, p value <0.05 was considered to be statistically significant. SPSS software version 17.0 was used.
resultsEach 10ng/ml decrease in Vitamin D level is associated with 7.25% greater odds of wheezing. Our study also suggests, exclusive breast feeding and delaying of complementary feeding beyond 6 months of age are significant predictors of Vitamin D deficiency and have indirect association with increased incidence of wheezing in children.
conclusionThe study concluded that Vitamin D deficiency is associated with increased risk of recurrent wheezing.
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