ArticleJournal of clinical and diagnostic research : JCDR2016
A Study on Polypharmacy and Potential Drug-Drug Interactions among Elderly Patients Admitted in Department of Medicine of a Tertiary Care Hospital in Puducherry.
Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Article
- Assessment of co-ingestion effects on poisoning patterns, drug-drug interactions, and adverse outcomes in acute toxic exposure.Toxicology reports · 2024Article
- Polypharmacy in chronic liver disease patients: Implications for disease severity, drug-drug interaction, and quality of life.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- Physical activity has a stronger correlation with arterial stiffness than strength, balance, or BMI in an older population.Frontiers in aging · 2023Article
- Overtreatment in elderly care: ethical considerations.Acta bio-medica : Atenei Parmensis · 2022Article
- An Up-to-Date Article Regarding Particularities of Drug Treatment in Patients with Chronic Heart Failure.Journal of clinical medicine · 2022Review
- Potential Drug-drug Interactions among Hospital Discharge Prescriptions in a Tertiary Care Centre of Nepal: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2022Article
- Drug-drug interactions among hospitalized elderly in patients at medical wards of Northwest Ethiopia's Comprehensive Specialized Hospitals: A multicenter observational study.SAGE open medicine · 2022Article
- Issues and challenges of polypharmacy in the elderly: A review of contemporary Indian literature.Journal of family medicine and primary care · 2021Review
- Napabucasin Drug-Drug Interaction Potential, Safety, Tolerability, and Pharmacokinetics Following Oral Dosing in Healthy Adult Volunteers.Clinical pharmacology in drug development · 2021Article
- Review
- Prevalence of Polypharmacy, Hyperpolypharmacy and Potentially Inappropriate Medication Use in Older Adults in India: A Systematic Review and Meta-Analysis.Frontiers in pharmacology · 2021Article
- Blood pressure and hypertension prevalence among oldest-old in China for 16 year: based on CLHLS.BMC geriatrics · 2019Article
- A multicentric cross-sectional study to characterize the scale and impact of polypharmacy in rural Indian communities, conducted as part of health workers training.Journal of family medicine and primary care · 2019Article
- Epidemiology of potential drug-drug interactions in elderly population admitted to critical care units of Peshawar, Pakistan.BMC pharmacology & toxicology · 2018Article
- Evaluation of Potential Drug-Drug Interactions with Medications Prescribed to Geriatric Patients in a Tertiary Care Hospital.Journal of aging research · 2018Article
- Potential drug-drug interactions among elderly patients admitted to medical ward of Ayder Referral Hospital, Northern Ethiopia: a cross sectional study.BMC research notes · 2016Article
- Evaluation of Medication Package Inserts in Iran.Journal of research in pharmacy practiceArticle
- Are drug-drug interactions a real clinical concern?Perspectives in clinical researchArticle
- Comparison of the extent and prevalence of prescription of potentially inappropriate medications prescribed to geriatric age group residing in old-age homes versus those receiving care from tertiary care hospital using Beers criteria.Perspectives in clinical researchArticle
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Authors and funding
3 authors.
Funding
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Abstract
introductionThe proportion of elderly population has been constantly increasing over last few years. Polypharmacy is unavoidable in the elderly as they often suffer from multiple co-morbidities. Potential drug-drug interaction due to polypharmacy and potential inappropriate medication among the elderly must be carefully assessed.
aimTo find out polypharmacy and potential drug-drug interactions among elderly patients admitted and discharged in Department of Medicine. MATERIALS AND
methodsThis study was carried out on 100 patients above 65 years of age both males and females. Data was collected through review of case sheets. Polypharmacy was observed based on admission and discharge prescriptions. Frequently occurring drug-drug interactions were assessed using online checks.
resultsMean number of drugs prescribed to patients on admission (7.61 ± 3.37) was more than that on discharge (5.48±2.46). More than half of these patients received 5 to 9 number of drugs. On admission 52.69% potential drug-drug interactions were observed and on discharge 52.91%. Most common drug interactions observed in both the groups were of moderate grade.
conclusionFrom the present study we can conclude that polypharmacy leads to more potential drug-drug interactions. To improve drug safety in this high-risk population, appropriate prescribing is very important.
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