ArticleJournal of clinical and diagnostic research : JCDR2016
Comparative Study of 5'-Nucleotidase Test in Various Liver Diseases.
Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Alterations in Adenylate Nucleotide Metabolism and Associated Lipid Peroxidation and Protein Oxidative Damage in Rat Kidneys Under Combined Acetaminophen Toxicity and Protein Deficiency.Antioxidants (Basel, Switzerland) · 2026Article
- Putative biomarkers of hepatic dysfunction in critically ill sepsis patients.Clinical and experimental medicine · 2025Article
- Mechanisms of sepsis-induced acute liver injury: a comprehensive review.Frontiers in cellular and infection microbiology · 2025Review
- Serum 5'-Nucleotidase as a Novel Predictor of Adverse Clinical Outcomes after Percutaneous Coronary Intervention in Patients with Coronary Artery Disease.Reviews in cardiovascular medicine · 2024Article
- Possible Role of Extracellular Vesicles in Hepatotoxicity of Acetaminophen.International journal of molecular sciences · 2022Article
- Hepatocellular carcinoma: Understanding molecular mechanisms for defining potential clinical modalities.World journal of hepatology · 2021Review
- Transforming growth factor-beta and liver injury in an arginine vasopressin-induced pregnant rat model.Clinical and experimental reproductive medicine · 2021Article
- Nanoparticle Drug Delivery Can Reduce the Hepatotoxicity of Therapeutic Cargo.Small (Weinheim an der Bergstrasse, Germany) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe liver regulates many important metabolic functions. The 5'-nucleotidase activity is increased in obstructive jaundice, parenchymal liver disease, and hepatic metastases.
aimThis study was conducted to assess the serum levels of 5'-nucleotidase on patients with viral hepatitis, alcoholic liver diseases and liver cirrhosis, moreover to make comparison to assess the degree of biliary involvement. MATERIALS AND
methodsA total of 60 male subjects (15 healthy controls and 45 case subjects) were enrolled, aged between 30 -50 years, each case group consisted of 15 male age-matched patients suffering with viral hepatitis, alcoholic liver disease (more than 10 years.) and liver cirrhosis. Serum 5'-nucleotidase was analyzed as per the standard laboratory procedure.
resultsThe 5'-nucleotidase levels were significantly raised in viral hepatitis, alcoholic liver disease and cirrhosis patients. The levels being 35.2±8.43, 29.87±3.94, and 24.07± 4.33 respectively as compared to healthy control (11±3.42) U/L.
conclusionSerum 5'-nucleotidase levels showed elevations in mean value of three fold in viral hepatitis, 2.5 folds elevation in alcoholic liver disease and two fold in cirrhosis as compared of healthy control subjects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.