ArticleEuropean heart journal. Quality of care & clinical outcomes2016
Long-term healthcare use and costs in patients with stable coronary artery disease: a population-based cohort using linked health records (CALIBER).
Article in European heart journal. Quality of care & clinical outcomes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 5 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The economic burden of ischaemic heart diseases on health systems: a systematic review.BMJ global health · 2025Pooled it
- Global comparison of the economic costs of coronary heart disease: a systematic review and meta-analysis.BMJ open · 2025Pooled it
- The effects and safety of testosterone replacement therapy for men with hypogonadism: the TestES evidence synthesis and economic evaluation.Health technology assessment (Winchester, England) · 2024Pooled it
- High-sensitivity troponin assays for early rule-out of acute myocardial infarction in people with acute chest pain: a systematic review and economic evaluation.Health technology assessment (Winchester, England) · 2021Pooled it
- A Systematic Review of Direct Cardiovascular Event Costs: An International Perspective.PharmacoEconomics · 2019Pooled it
- Tai Chi Is a Promising Exercise Option for Patients With Coronary Heart Disease Declining Cardiac Rehabilitation.Journal of the American Heart Association · 2017Trial
- Using a Markov Model and Real-World Evidence to Identify the Most Cost-Effective Cholesterol Treatment Escalation Threshold for the Secondary Prevention of Cardiovascular Disease.Applied health economics and health policy · 2025Article
- Digital variance angiography in patients undergoing lower limb arterial recanalization: cost-effectiveness analysis within the English healthcare setting.Journal of comparative effectiveness research · 2024Article
- Hospitalization expenses of coronary heart disease inpatients in China: evidence from two hospitals in Ningxia Hui autonomous region.Frontiers in public health · 2024Article
- Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis.Health technology assessment (Winchester, England) · 2023Article
- Genetic, sociodemographic, lifestyle, and clinical risk factors of recurrent coronary artery disease events: a population-based cohort study.European heart journal · 2023Article
- Prediction Models for Individual-Level Healthcare Costs Associated with Cardiovascular Events in the UK.PharmacoEconomics · 2023Article
- Direct medical costs of ischemic heart disease in urban Southern China: a 5-year retrospective analysis of an all-payer health claims database in Guangzhou City.Frontiers in public health · 2023Article
- Future Offspring Costs in Economic Evaluation.PharmacoEconomics · 2022Article
- Economic Analysis of the CADScor System for Ruling Out Coronary Artery Disease in England.PharmacoEconomics - open · 2022Article
- Modelling the Economic Impact of Reducing Loneliness in Community Dwelling Older People in England.International journal of environmental research and public health · 2021Article
- Psychometric Features of the Polish Version of TSK Heart in Elderly Patients with Coronary Artery Disease.Medicina (Kaunas, Lithuania) · 2020Article
- Intensified ambulatory cardiology care: effects on mortality and hospitalisation-a comparative observational study.Scientific reports · 2020Observational
- DyeVert™ PLUS EZ System for Preventing Contrast-Induced Acute Kidney Injury in Patients Undergoing Diagnostic Coronary Angiography and/or Percutaneous Coronary Intervention: A UK-Based Cost-Utility Analysis.PharmacoEconomics - open · 2020Article
- Association of treatments for acute myocardial infarction and survival for seven common comorbidity states: a nationwide cohort study.BMC medicine · 2020Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
aimsTo examine long-term healthcare utilization and costs of patients with stable coronary artery disease (SCAD). METHODS AND
resultsLinked cohort study of 94 966 patients with SCAD in England, 1 January 2001 to 31 March 2010, identified from primary care, secondary care, disease, and death registries. Resource use and costs, and cost predictors by time and 5-year cardiovascular disease (CVD) risk profile were estimated using generalized linear models. Coronary heart disease hospitalizations were 20.5% in the first year and 66% in the year following a non-fatal (myocardial infarction, ischaemic or haemorrhagic stroke) event. Mean healthcare costs were £3133 per patient in the first year and £10 377 in the year following a non-fatal event. First-year predictors of cost included sex (mean cost £549 lower in females), SCAD diagnosis (non-ST-elevation myocardial infarction cost £656 more than stable angina), and co-morbidities (heart failure cost £657 more per patient). Compared with lower risk patients (5-year CVD risk 3.5%), those of higher risk (5-year CVD risk 44.2%) had higher 5-year costs (£23 393 vs. £9335) and lower lifetime costs (£43 020 vs. £116 888).
conclusionPatients with SCAD incur substantial healthcare utilization and costs, which varies and may be predicted by 5-year CVD risk profile. Higher risk patients have higher initial but lower lifetime costs than lower risk patients as a result of shorter life expectancy. Improved cardiovascular survivorship among an ageing CVD population is likely to require stratified care in anticipation of the burgeoning demand.
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