Evidence map›Paper›PMID 27042323›Full record

ArticleOpen heart

Excess short-term mortality in women after isolated coronary artery bypass graft surgery.

Giovanni Filardo, Baron L Hamman, Benjamin D Pollock, Briget da Graca, Danielle M Sass, Teresa K Phan, James Edgerton, Syma L Prince, W Steves Ring

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Review
  8. Impact of gender on 10-year outcome after coronary artery bypass grafting.Interactive cardiovascular and thoracic surgery · 2021
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Giovanni FilardoDepartment of Epidemiology , Office of the Chief Quality Officer, Baylor Scott & White Health , Dallas, Texas , USA.
Baron L HammanDepartment of Cardiothoracic Surgery , Baylor Heart and Vascular Institute, Baylor University Medical Center , Dallas, Texas , USA.
Benjamin D PollockDepartment of Epidemiology , Office of the Chief Quality Officer, Baylor Scott & White Health , Dallas, Texas , USA.
Briget da GracaDepartment of Epidemiology , Office of the Chief Quality Officer, Baylor Scott & White Health , Dallas, Texas , USA.
Danielle M SassDepartment of Epidemiology , Office of the Chief Quality Officer, Baylor Scott & White Health , Dallas, Texas , USA.
Teresa K PhanDepartment of Epidemiology , Office of the Chief Quality Officer, Baylor Scott & White Health , Dallas, Texas , USA.
James EdgertonThe Heart Hospital Baylor , Plano, Texas , USA.
Syma L PrinceCardiopulmonary Research Science & Technology Institute , Dallas, Texas , USA.
W Steves RingDepartment of Cardiothoracic Surgery , UT Southwestern Medical Center , Dallas, Texas , USA.
Baylor Scott & White Health · USBaylor University Medical Center · USCardiopulmonary Research Science and Technology Institute · USHeart Hospital Baylor Plano · USThe University of Texas Southwestern Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFemale sex is considered a risk factor for adverse outcomes following isolated coronary artery bypass graft (CABG) surgery. We assessed the association between sex and short-term mortality following isolated CABG, and estimated the 'excess' deaths occurring in women.

methodsShort-term mortality was investigated in 13 327 consecutive isolated CABG patients in North Texas between January 2008 and December 2012. The association between sex and CABG short-term mortality, and the excess deaths among women were assessed via a propensity-adjusted (by Society of Thoracic Surgeons-recognised risk factors) generalised estimating equations model approach.

resultsShort-term mortality was significantly higher in women than men (adjusted OR=1.39; 95% CI 1.04 to 1.86; p=0.027). This significantly greater risk translates into 35 'excess' deaths among women included in this study (>10% of the total 343 deaths in the study cohort) and into 392 'excess' deaths among the ∼40 000 women undergoing isolated CABG in the USA each year.

conclusionsThe higher risk associated with female sex lead to 35 'excess' deaths in women in this study cohort (over 10% of the total deaths) and to 392 'excess' deaths among women undergoing isolated CABG in the USA each year. Further research is needed to assess the causal mechanisms underlying this sex-related difference. Results of such work could inform the development and implementation of sex-specific treatment and management strategies to reduce women's mortality following CABG. Based on our results, if such work brought women's short-term mortality into line with men's, total short-term mortality could be reduced by up to 10%.

Indexed as

QUALITY OF CARE AND OUTCOMES

Identifiers

PMID27042323
PMCPMC4809184
OpenAlexW2308483384

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.