Evidence map›Paper›PMID 27042317›Full record

ReviewOpen heart

Nutritional strategies for skeletal and cardiovascular health: hard bones, soft arteries, rather than vice versa.

James H O'Keefe, Nathaniel Bergman, Pedro Carrera-Bastos, Maélan Fontes-Villalba, James J DiNicolantonio, Loren Cordain

Abstract readReview
In one paragraph

Review in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Postmenopausal women with osteoporosis consume high amounts of vegetables but insufficient dairy products and calcium to benefit from their virtues: the CoLaus/OsteoLaus cohort.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

James H O'KeefeSaint Luke's Mid America Heart Institute , Kansas City, Missouri , USA.
Nathaniel BergmanCleveland Clinic Foundation , Center for Functional Medicine , Cleveland, Ohio , USA.
Pedro Carrera-BastosCenter for Primary Health Care Research , Department of Clinical Sciences, Faculty of Medicine at Lund University , Malmö , Sweden.
Maélan Fontes-VillalbaCenter for Primary Health Care Research , Department of Clinical Sciences, Faculty of Medicine at Lund University , Malmö , Sweden.ORCID 0000-0001-6714-6133
James J DiNicolantonioSaint Luke's Mid America Heart Institute , Kansas City, Missouri , USA.
Loren CordainEmeritus Professor of Nutritional Science , Colorado State University , Fort Collins, Colorado , USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The focus of this paper is to explore better strategies for optimising bone strength and reducing risk of fracture, while at the same time decreasing risk of cardiovascular disease. The majority of Americans do not consume the current recommended dietary allowance for calcium, and the lifetime risk of osteoporosis is about 50%. However, traditional mononutrient calcium supplements may not be ideal. We comprehensively and systematically reviewed the scientific literature in order to determine the optimal dietary strategies and nutritional supplements for long-term skeletal health and cardiovascular health. To summarise, the following steps may be helpful for building strong bones while maintaining soft and supple arteries: (1) calcium is best obtained from dietary sources rather than supplements; (2) ensure that adequate animal protein intake is coupled with calcium intake of 1000 mg/day; (3) maintain vitamin D levels in the normal range; (4) increase intake of fruits and vegetables to alkalinise the system and promote bone health; (5) concomitantly increase potassium consumption while reducing sodium intake; (6) consider increasing the intake of foods rich in vitamins K1 and K2; (7) consider including bones in the diet; they are a rich source of calcium-hydroxyapatite and many other nutrients needed for building bone.

Indexed as

CALCIUMCV RISKQUALITY OF CARE AND OUTCOMESVITAMIN D

Identifiers

PMID27042317
PMCPMC4809188

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.