ArticleAnnals of general psychiatry2016
Relationship between the lesion location of acute ischemic stroke and early depressive symptoms in Japanese patients.
Article in Annals of general psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- The association between lesion location, sex and poststroke depression: Meta-analysis.Brain and behavior · 2017Pooled it
- Imaging Markers of Post-Stroke Depression and Apathy: a Systematic Review and Meta-Analysis.Neuropsychology review · 2017Pooled it
- Development and interpretation of a machine learning risk prediction model for post-stroke depression in a Chinese population.Scientific reports · 2025Article
- Loss of empathy in stroke.Frontiers in psychology · 2024Article
- Upregulation of S100A8 in peripheral blood mononuclear cells from patients with depression treated with SSRIs: a pilot study.Proteome science · 2023Article
- Large-scale lesion symptom mapping of depression identifies brain regions for risk and resilience.Brain : a journal of neurology · 2023Article
- In-Hospital Symptoms of Depression and Anxiety are Strong Risk Factors for Post-Stroke Depression 90 Days After Ischemic Stroke.The Neurohospitalist · 2023Article
- Social isolation in patients with chronic limb-threatening ischemia: a cross-sectional study.Scientific reports · 2023Article
- A Comparative Study of Regional Cerebral Blood Flow Asymmetry Index in Stroke Patients with or without Poststroke Depression UsingWorld journal of nuclear medicine · 2022Article
- Article
- Understanding Why Post-Stroke Depression May Be the Norm Rather Than the Exception: The Anatomical and Neuroinflammatory Correlates of Post-Stroke Depression.Journal of clinical medicine · 2021Review
- Association of Cerebral Artery Stenosis With Post-stroke Depression at Discharge and 3 Months After Ischemic Stroke Onset.Frontiers in psychiatry · 2020Article
- Post-Stroke Depression.Materia socio-medica · 2019Article
- The association between mean platelet volume levels and poststroke depression.Brain and behavior · 2018Article
- Lower cognitive control network connectivity in stroke participants with depressive features.Translational psychiatry · 2018Article
- Changes in motor function, cognition, and emotion-related behavior after right hemispheric intracerebral hemorrhage in various brain regions of mouse.Brain, behavior, and immunity · 2018Article
- Risk Factors for Post-stroke Depression: A Meta-analysis.Frontiers in aging neuroscience · 2017Review
- Post-Stroke Depression: Impact of Lesion Location and Methodological Limitations-A Topical Review.Frontiers in neurology · 2017Review
- Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundApproximately one-third of stroke survivors suffer from post-stroke depression (PSD) in the acute or chronic stages. The presence of PSD in the acute stage after stroke is reportedly associated with poor patient prognosis; therefore, early recognition and treatment of PSD may alleviate these consequences. The aim of the current study was to examine the relationship between the lesion location and the presence of early depressive symptoms after acute ischemic stroke in Japanese patients.
methodsOur study included 421 patients who suffered from acute ischemic stroke. On the day of admission, the lesion location was determined using magnetic resonance imaging (MRI). Stroke severity was measured on the seventh day of hospitalization withat the National Institutes of Health Stroke Scale (NIHSS). On the tenth day of hospitalization, depressive symptoms were measured and functional assessments were performed with the Japan Stroke Scale (Depression Scale) (JSS-D) and functional independence measure (FIM), respectively.
resultsA total of 71 subjects (16.9 %) were diagnosed with depression. According to the multiple logistic regression analysis, the infarcts located at frontal and temporal lobes were found to be a significant independent risk factor of early depressive symptoms in the acute stage of stroke.
conclusionsPatients suffering from acute ischemic stroke, particularly in the frontal and temporal lobes, should be carefully assessed to detect and treat early depressive symptoms; such treatment may improve patient outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.