Observational studyInternational journal of chronic obstructive pulmonary disease2016
POPE study: rationale and methodology of a study to phenotype patients with COPD in Central and Eastern Europe.
Observational study in International journal of chronic obstructive pulmonary disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02119494 (POPE-Study), which is not on this map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
POPE-Study: Phenotypes Of COPD in Central and Eastern Europe Study
Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Article
- RETRO-POPE: A Retrospective, Multicenter, Real-World Study of All-Cause Mortality in COPD.International journal of chronic obstructive pulmonary disease · 2023Article
- Chronic obstructive pulmonary disease phenotypes in Turkey: the COPET study-a national, multicenter cross-sectional observational study.Turkish journal of medical sciences · 2022Observational
- Chronic obstructive pulmonary disease phenotypes: imprint on pharmacological and non-pharmacological therapy.Annals of translational medicine · 2020Review
- Phenotypes of COPD in an Austrian population : National data from the POPE study.Wiener klinische Wochenschrift · 2018Article
- Distribution and characteristics of COPD phenotypes - results from the Polish sub-cohort of the POPE study.International journal of chronic obstructive pulmonary disease · 2018Observational
- Inhaled therapies in patients with moderate COPD in clinical practice: current thinking.International journal of chronic obstructive pulmonary disease · 2018Review
- Mortality in COPD patients according to clinical phenotypes.International journal of chronic obstructive pulmonary disease · 2018Observational
- Phenotypes of COPD patients with a smoking history in Central and Eastern Europe: the POPE Study.The European respiratory journal · 2017Observational
- Characteristics of COPD patients according to GOLD classification and clinical phenotypes in the Russian Federation: the SUPPORT trial.International journal of chronic obstructive pulmonary disease · 2017Observational
- Diagnosing COPD: advances in training and practice - a systematic review.Advances in medical education and practice · 2016Review
- COPD patients' characteristics, usual care, and adherence to guidelines: the Greek UNLOCK study.International journal of chronic obstructive pulmonary diseaseArticle
- Geographic variations of the prevalence and distribution of COPD phenotypes in Spain: "the ESPIRAL-ES study".International journal of chronic obstructive pulmonary diseaseObservational
Corrections and comments
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Authors and funding
9 authors at 9 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionChronic obstructive pulmonary disease (COPD) constitutes a major health challenge in Central and Eastern European (CEE) countries. However, clinical phenotypes, symptom load, and treatment habits of patients with COPD in CEE countries remain largely unknown. This paper provides a rationale for phenotyping COPD and describes the methodology of a large study in CEE. METHODS/
designThe POPE study is an international, multicenter, observational cross-sectional survey of patients with COPD in CEE. Participation in the study is offered to all consecutive outpatients with stable COPD in 84 centers across the CEE region if they fulfill the following criteria: age >40 years, smoking history ≥10 pack-years, a confirmed diagnosis of COPD with postbronchodilator FEV1/FVC <0.7, and absence of COPD exacerbation ≥4 weeks. Medical history, risk factors for COPD, comorbidities, lung function parameters, symptoms, and pharmaceutical and nonpharmaceutical treatment are recorded. The POPE project is registered in ClinicalTrials.gov with the identifier NCT02119494. OUTCOMES: The primary aim of the POPE study was to phenotype patients with COPD in a real-life setting within CEE countries using predefined classifications. Secondary aims of the study included analysis of differences in symptoms, and diagnostic and therapeutic behavior in participating CEE countries.
conclusionThere is increasing acceptance toward a phenotype-driven therapeutic approach in COPD. The POPE study may contribute to reveal important information regarding phenotypes and therapy in real-life CEE.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.