Evidence map›Paper›PMID 27042043›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2016

Cognitive status among patients with chronic obstructive pulmonary disease.

Carlos Roncero, Ana Isabel Campuzano, Jose Antonio Quintano, Jesús Molina, Joselín Pérez, Marc Miravitlles

Abstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Real-Life Effectiveness of Aclidinium/Formoterol on COPD Control: The REDACT Observational Study.International journal of chronic obstructive pulmonary disease · 2026
    Observational
  3. Does Cognitive Function Influence the Benefits of Multicomponent Team Interventions?Journal of the American Medical Directors Association · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Enhanced risk of traumatic brain injury in patients with chronic obstructive pulmonary disease.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2020
    Article
  13. Observational
  14. Moderate-to-Severe Obstructive Sleep Apnea and Cognitive Function Impairment in Patients with COPD.International journal of chronic obstructive pulmonary disease · 2020
    Article
  15. Article
  16. Epidemiology of Dementia in Elderly Chronic Obstructive Pulmonary Disease Patients Living in China's Northwestern High-Elevation Area.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  17. Observational
  18. Article
  19. Depressive status explains a significant amount of the variance in COPD assessment test (CAT) scores.International journal of chronic obstructive pulmonary disease · 2018
    Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carlos RonceroAddiction and Dual Diagnosis Unit, Psychiatry Department, Vall d'Hebron Hospital-ASPB. Ciber de Salud Mental (CIBERSAM) and Department of Psychiatry and Legal Medicine, Universidad Autónoma de Barcelona, Barcelona, Spain.
Ana Isabel CampuzanoMedical Department, Grupo Ferrer, Barcelona, Spain.
Jose Antonio QuintanoPrimary Care Center Lucena I, Lucena, Cordoba, Spain.
Jesús MolinaPrimary Care Center Francia, Dirección Asistencial Oeste, Madrid, Spain.
Joselín PérezMedical Department, Grupo Ferrer, Barcelona, Spain.
Marc MiravitllesDepartment of Pneumology, Hospital Universitari Vall d'Hebron. Ciber de Enfermedades Respiratorias (CIBERES), Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe investigated the association between cognitive impairment and chronic obstructive pulmonary disease (COPD), taking into account demographic and clinical variables evaluated during routine practice. PATIENTS AND

methodsWe performed a post hoc analysis of a cross-sectional study that included subjects with stable COPD. Sociodemographic and clinical information was recorded using the Body mass index, airflow Obstruction, Dyspnea and Exacerbations index and the Charlson comorbidity index. Cognitive performance was studied by the mini-mental state examination, with a score less than 27 indicating clinical impairment. Depressive symptoms, physical activity, and quality of life (EuroQoL-5 dimensions and COPD Assessment Test) were also evaluated.

resultsThe analysis included 940 subjects. The prevalence of cognitive impairment was 39.4%. Multivariate logistic regression models revealed that cognitive impairment was associated with educational level (odds ratio [OR] =0.096, 95% confidence interval [CI] =0.011-0.447) and poorer quality of life measured by the EuroQoL-5 dimensions social tariff (OR =0.967, 95% CI =0.950-0.983). When questionnaires were not included in the analysis, cognitive impairment was associated with educational level (OR =0.063, 95% CI =0.010-0.934), number of exacerbations (OR =11.070, 95% CI =1.450-84.534), Body mass index, airflow Obstruction, Dyspnea and Exacerbations index score (OR =1.261, 95% CI =1.049-1.515), and the Charlson comorbidity index (OR =1.412, 95% CI =1.118-1.783).

conclusionCognitive impairment is common in COPD and is associated with low educational level, higher disease severity, and increased comorbidity. This could have therapeutic implications for this population.

Indexed as

AdultAgedAged, 80 and overCognition DisordersCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalencePulmonary Disease, Chronic Obstructivechronic obstructive pulmonary diseasecognitive functioncomorbiditydepressionmini-mental state examinationquality of life

Identifiers

PMID27042043
PMCPMC4801148

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.