ReviewChinese journal of cancer research = Chung-kuo yen cheng yen chiu2016
The evolving Gleason grading system.
Review in Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Assessing the relationship between cardiometabolic diseases and the risk of developing aggressive prostate cancer: a systematic review and meta-analysis.BMC cancer · 2025Pooled it
- Systematic review and meta-analysis of the associations between body mass index, prostate cancer, advanced prostate cancer, and prostate-specific antigen.Cancer causes & control : CCC · 2020Pooled it
- Possible association between androgenic alopecia and risk of prostate cancer and testicular germ cell tumor: a systematic review and meta-analysis.BMC cancer · 2018Pooled it
- Dosimetry ofMolecules (Basel, Switzerland) · 2019Trial
- Benchmarking copy number alteration inference methods for spatial transcriptomics.Nature communications · 2026Article
- PTEN Protein Loss in Diagnostic Prostate Biopsies Is Associated with Gleason Score Upgrading in Radical Prostatectomy.Cancers · 2026Article
- Slide-free FIBI histology for improved quantitative vascular network analysis in breast cancer: Integrating vessel geometry and topology metrics.Journal of pathology informatics · 2026Article
- Prostate Cancer Treatment: Cryoablation in Context.Cancers · 2026Review
- PANDA-PLUS: Improved dataset of prostate whole slide images from PANDA Challenge with pixel-level expert annotations.Journal of pathology informatics · 2026Article
- Tackling the progression of benign prostatic hyperplasia/benign prostatic obstruction progression: Deobstructing within the "window of curability" (a hypothesis-generating review).Current urology · 2025Article
- Pathologist-like explainable AI for interpretable Gleason grading in prostate cancer.Nature communications · 2025Article
- Interpretable machine learning model predicts 1-year inguinal hernia risk after robot-assisted radical prostatectomy.Journal of robotic surgery · 2025Article
- Evaluation of potential prognostic significance of JUNB in human prostate cancer: a bioinformatic and histopathological study.Journal of pathology and translational medicine · 2025Article
- Artificial Intelligence-Assisted Biparametric MRI for Detecting Prostate Cancer-A Comparative Multireader Multicase Accuracy Study.Journal of clinical medicine · 2025Article
- Impact of circActa histochemica et cytochemica · 2025Article
- Association of absolute amount of pattern 4 disease on prostate biopsy with oncologic outcomes in intermediate-risk prostate cancer A systematic review.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025Review
- The application of multi-instance learning based on feature reconstruction and cross-mixing in the Gleason grading of prostate cancer from whole-slide images.Quantitative imaging in medicine and surgery · 2025Article
- Prognostic Significance of Ki67 Expression in Prostate Cancer in Nigerians: A Single-Center Study.Cureus · 2025Article
- The impact of biopsy core length on the discrepancy in Gleason scores between biopsy and radical prostatectomy specimen.BJUI compass · 2025Article
- Development of a deep learning system for predicting biochemical recurrence in prostate cancer.BMC cancer · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Gleason grading system for prostate adenocarcinoma has evolved from its original scheme established in the 1960s-1970s, to a significantly modified system after two major consensus meetings conducted by the International Society of Urologic Pathology (ISUP) in 2005 and 2014, respectively. The Gleason grading system has been incorporated into the WHO classification of prostate cancer, the AJCC/UICC staging system, and the NCCN guidelines as one of the key factors in treatment decision. Both pathologists and clinicians need to fully understand the principles and practice of this grading system. We here briefly review the historical aspects of the original scheme and the recent developments of Gleason grading system, focusing on major changes over the years that resulted in the modern Gleason grading system, which has led to a new "Grade Group" system proposed by the 2014 ISUP consensus, and adopted by the 2016 WHO classification of tumours of the prostate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.