ArticleContemporary clinical dentistry
In vivo comparison of cavity disinfection efficacy with APF gel, Propolis, Diode Laser, and 2% chlorhexidine in primary teeth.
Article in Contemporary clinical dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Antibacterial Effect of Nano Silver Fluoride Versus Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique: A Randomized Clinical Trial
Evaluation of The Antibacterial Effect of Laser Diode and Zinc Oxide Nano-particles on Streptococcus Mutans Bacteria Used as Cavity Disinfectants in Deep Carious Lesions : A Randomized Controlled Clinical Trial
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Propolis-containing formulations in caries prevention - a systematic review and meta-analysis.Clinical oral investigations · 2026Pooled it
- Article
- Propolis Stands out as a Multifaceted Natural Product: Meta-Analysis on Its Sources, Bioactivities, Applications, and Future Perspectives.Life (Basel, Switzerland) · 2025Review
- Effectiveness of Dental Restorative Materials in the Atraumatic Treatment of Carious Primary Teeth in Pediatric Dentistry: A Systematic Review.Children (Basel, Switzerland) · 2025Review
- Evaluating the effectiveness of various disinfectants in deep carious lesions: AnJournal of conservative dentistry and endodontics · 2025Article
- Efficacy of non -thermal pressure plasma versus other modalities for disinfection of primary root canals.BMC oral health · 2025Article
- Investigations of the Antimicrobial Effectiveness of Different Disinfection Protocols Against Endodontic Pathogens in Root Canal Systems.Journal of pharmacy & bioallied sciences · 2024Article
- Article
- Efficacy of antiseptics and chemomechanical methods for dentin caries lesions: A systematic review with GRADE approach.Frontiers in oral health · 2023Review
- Efficacy of diode laser application versus silver diamine fluoride (SDF) as a modification of Hall technique in primary teeth.The Saudi dental journal · 2022Article
- The effects of cavity disinfection on the nanoleakage of compomer restorations: an in vitro study.European oral research · 2020Article
- Propolis: A natural biomaterial for dental and oral healthcare.Journal of dental research, dental clinics, dental prospects · 2017Review
- Evaluation of Antibacterial Effect of Propolis and its Application in Mouthwash Production.Frontiers in dentistryArticle
- Effect of low-level diode laser onJournal of oral biology and craniofacial researchArticle
- Evaluation of temperature rise and efficacy of cavity disinfection with diode laser: AnJournal of conservative dentistry : JCDArticle
- Efficacy of Liquorice and Propolis Extract Used as Cavity Cleaning Agents againstInternational journal of clinical pediatric dentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe survival of atraumatic restorative treatment (ART) restorations would be enhanced if near total elimination of cariogenic microorganisms could be done in the process of cavity cleaning before placing a restoration. Thus, use of disinfecting agents for achieving this goal could herald a new beginning in the field of contemporary dentistry.
aimTo assess and compare the cavity disinfection efficacy of APF gel, Brazilian Propolis, Diode Laser, and 2% chlorhexidine (CHX). MATERIALS AND
methodsThe study was a randomized, single blinded, parallel grouped, active controlled trial. Eighty primary molars in 68 children with cavitated dentinal occlusal caries were randomly assigned into four groups (20 teeth each) Group I: APF gel; Group II: Propolis; Group III: Diode Laser, and Group IV: 2% CHX (control). After cavity preparation using ART procedure, dentinal samples collected before and after disinfection with respective agent of the group. These samples were subjected to microbiological evaluation, for total viable count (TVC) on blood agar, Streptococcus mutans on mutans-sanguis (MS) agar, and Lactobacilli (LB) on Rogosa agar.
resultsIntragroup comparison (Wilcoxon signed rank test) showed significant reductions in TVC, MS, and LB counts in all the groups. Pairwise Mann-Whitney test showed APF gel had least bacterial reductions among the agents tested.
conclusionThis study illustrated the need for cavity disinfection. Diode Laser and Brazilian Propolis are equally effective as 2% CHX in cavity disinfection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.